NINDS offers a phased R61/R33 grant for secondary data analysis of existing clinical datasets. This grant supports multidisciplinary teams exploring neurological disorders by harmonizing and curating data from two or more multi-site projects. The initial R61 phase mandates comprehensive data harmonization, assessed by Go/No-go metrics. Successful completion transitions to the R33 phase for in-depth data analyses. Consistent with FAIR principles, awardees must openly catalog harmonization and analysis tools, and provide controlled access to curated datasets. This grant aims to maximize existing clinical data utility for NINDS research.
Opportunity ID: 345706
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-23-089 |
| Funding Opportunity Title: | Data Harmonization, Curation and Secondary Analysis of Existing Clinical Datasets (R61/R33 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.310 — Trans-NIH Research Support |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jan 31, 2023 |
| Last Updated Date: | Jan 31, 2023 |
| Original Closing Date for Applications: | Mar 14, 2024 |
| Current Closing Date for Applications: | Mar 14, 2024 |
| Archive Date: | Apr 19, 2024 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | City or township governments Others (see text field entitled “Additional Information on Eligibility” for clarification) State governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Public housing authorities/Indian housing authorities Public and State controlled institutions of higher education Private institutions of higher education For profit organizations other than small businesses County governments Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Special district governments Independent school districts |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This FOA invites applications from multidisciplinary teams to perform secondary data analysis, using existing datasets from two or more multi-site clinical research projects, to address scientific and clinical hypotheses relevant to neurological disorders and conditions within the NINDS mission. In this phased funding mechanism, applications are required to systematically and comprehensively perform cross-project data harmonization and curation, assessed using Go/No-go data-quality metrics, prior to funding of the second phase of data analyses. Consistent with the FAIR (findable, accessible, interoperable and reusable) data principles, this funding opportunity expects open-source cataloging of the processes and tools used for harmonization, curation, and analysis, as well as controlled access to the curated datasets. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/pa-files/PAR-23-089.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 345706 Full Announcement-PAR-23-089 -> PAR-23-089-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00279595 | Feb 14, 2023 | Mar 14, 2024 | View |
Package 1
Mandatory forms
345706 RR_SF424_5_0-5.0.pdf
345706 PHS398_CoverPageSupplement_5_0-5.0.pdf
345706 RR_OtherProjectInfo_1_4-1.4.pdf
345706 PerformanceSite_4_0-4.0.pdf
345706 RR_KeyPersonExpanded_4_0-4.0.pdf
345706 RR_Budget_3_0-3.0.pdf
345706 PHS398_ResearchPlan_5_0-5.0.pdf
345706 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
345706 RR_SubawardBudget30_3_0-3.0.pdf
345706 PHS_AssignmentRequestForm_3_0-3.0.pdf
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