The National Institute of Neurological Disorders and Stroke (NINDS) is offering this grant to establish a Coordinating Center for its small vessel vascular contributions to cognitive impairment and dementia (VCID) biomarkers consortium. This grant is for completing the clinical validation of biomarkers developed in its initial phase. The Coordinating Center will provide essential administrative and data management infrastructure, coordinating consortium activities and managing de-identified clinical data. This support drives biomarker validation for future large-scale clinical trials with diverse populations. Ultimately, this aims for breakthroughs in VCID understanding and treatment.
Opportunity ID: 335651
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-NS-22-017 |
| Funding Opportunity Title: | Small Vessel VCID Biomarkers Validation Consortium Coordinating Center (U24 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.853 — Extramural Research Programs in the Neurosciences and Neurological Disorders |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Sep 10, 2021 |
| Last Updated Date: | Sep 10, 2021 |
| Original Closing Date for Applications: | Nov 12, 2021 |
| Current Closing Date for Applications: | Nov 12, 2021 |
| Archive Date: | Dec 18, 2021 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments For profit organizations other than small businesses Small businesses Special district governments Native American tribal governments (Federally recognized) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Native American tribal organizations (other than Federally recognized tribal governments) County governments Private institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Independent school districts Public and State controlled institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this funding opportunity announcement (FOA) is to have an open competition to support a Coordinating Center for the next phase of the NINDS small vessel vascular contributions to cognitive impairment and dementia (VCID) biomarkers consortium. The original consortium was established under RFA-NS-16-019 and RFA-NS-16-020. The goal of the next phase, under this FOA (Coordinating Center) and RFA-NS-20-005 (sites), is to complete clinical validation of biomarkers initially developed during the first 5-year funding cycle of this program. The Coordinating Center will consist of: (i) an Administrative Core responsible for organizing, coordinating and administratively driving Consortium activities; and (ii) a Data Core that will coordinate, receive, collect, and share data, including de-identified clinical data. The Coordinating Center will provide infrastructure and expertise to drive the consortium administratively and contribute scientifically to validation of biomarkers with specified context of use for future clinical trials, including in large phase III trials, with general and diverse populations, and for generating scientific breakthroughs in our understanding and treatment of VCID. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-NS-22-017.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
OERWebmaster03@od.nih.gov Email:OERWebmaster03@od.nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster OERWebmaster03@od.nih.gov Email: OERWebmaster03@od.nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-G | Use for due dates on or after January 25, 2022 | PKG00269634 | Oct 27, 2021 | Nov 12, 2021 | View | |
| FORMS-F | Use for due dates on or before January 24, 2022 | PKG00268894 | Oct 12, 2021 | Jan 24, 2022 | View |
Package 1
Mandatory forms
335651 RR_SF424_5_0-5.0.pdf
335651 PHS398_CoverPageSupplement_5_0-5.0.pdf
335651 RR_OtherProjectInfo_1_4-1.4.pdf
335651 PerformanceSite_4_0-4.0.pdf
335651 RR_KeyPersonExpanded_4_0-4.0.pdf
335651 RR_Budget_3_0-3.0.pdf
335651 PHS398_ResearchPlan_4_0-4.0.pdf
335651 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
335651 RR_SubawardBudget30_3_0-3.0.pdf
335651 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 2
Mandatory forms
335651 RR_SF424_2_0-2.0.pdf
335651 PHS398_CoverPageSupplement_5_0-5.0.pdf
335651 RR_OtherProjectInfo_1_4-1.4.pdf
335651 PerformanceSite_2_0-2.0.pdf
335651 RR_KeyPersonExpanded_2_0-2.0.pdf
335651 RR_Budget_1_4-1.4.pdf
335651 PHS398_ResearchPlan_4_0-4.0.pdf
335651 PHSHumanSubjectsAndClinicalTrialsInfo_2_0-2.0.pdf
Optional forms
335651 RR_SubawardBudget30_1_4-1.4.pdf
335651 PHS_AssignmentRequestForm_3_0-3.0.pdf
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