Office of Research Integrity (ORI) Grant: Enhancing Research Integrity and Preventing Misconduct

The Office of Research Integrity (ORI) is offering this FY25 grant to support Public Health Service (PHS)-funded institutions in fostering a strong research environment. This grant is for developing and evaluating programs that promote responsible conduct, enhance research integrity, and prevent misconduct. It supports empirical research into societal, organizational, behavioral, group, and individual factors influencing integrity in research. The aim is to identify the root causes of research misconduct and the driving factors for integrity, aligning with ORI’s mission to support education and outreach. This initiative helps institutions comply with regulations and ensures the ethical conduct of biomedical and behavioral research and training.

Opportunity ID: 355826

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General Information

Document Type:	Grants Notice
Funding Opportunity Number:	IR-ORI-25-003
Funding Opportunity Title:	FY25 Ensuring Research Integrity – Program Development and Evaluation Program (PDE)
Opportunity Category:	Discretionary
Opportunity Category Explanation:	–
Funding Instrument Type:	Grant
Category of Funding Activity:	Science and Technology and other Research and Development
Category Explanation:	–
Expected Number of Awards:	2
Assistance Listings:	93.085 — Research on Research Integrity
Cost Sharing or Matching Requirement:	No
Version:	Synopsis 4
Posted Date:	Jul 03, 2025
Last Updated Date:	Jul 14, 2025
Original Closing Date for Applications:	Jul 30, 2025 No Explanation
Current Closing Date for Applications:	Jul 30, 2025 No Explanation
Archive Date:	Aug 29, 2025
Estimated Total Program Funding:	$500,000
Award Ceiling:	$250,000
Award Floor:	$150,000

Eligibility

Eligible Applicants:

County governments
Public housing authorities/Indian housing authorities
Individuals
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
State governments
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Native American tribal governments (Federally recognized)
Small businesses
Special district governments
For profit organizations other than small businesses
Native American tribal organizations (other than Federally recognized tribal governments)
Independent school districts
Public and State controlled institutions of higher education
City or township governments
Private institutions of higher education

Additional Information on Eligibility:

Universities, hospitals, laboratories, other public or private institutions, and individuals are eligible to apply for an award under this announcement.
Faith-based organizations and community-based organizations are eligible to apply.
American Indian, Alaska Native, Native Hawaiian, and Pacific Islander organizations are eligible to apply.

Additional Information

Agency Name:	Office of the Assistant Secretary for Health
Description:	The Office of Research Integrity anticipates making award(s) for Fiscal Year (FY) 2025 under the authority of 42 U.S.C. § 241 (Section 301 of the Public Health Service Act). Institutions applying for or receiving Public Health Service (PHS) support for biomedical or behavioral research, biomedical or behavioral research training, or activities related to that research or research training are required to foster a research environment that promotes research integrity and the responsible conduct of research, discourages research misconduct, and deals promptly with allegations or evidence of possible research misconduct.” 42 C.F.R. § 93.300(c). Core to ORI’s mission is the support of education and outreach activities that aid PHS-funded research institutions in their efforts “to teach the responsible conduct of research, promote research integrity, prevent research misconduct, and . . . respond effectively to allegations of research misconduct[.]” (65 Fed. Reg. 30,600, 30,601 (May 12, 2000)). Our Research on Research Integrity Grant Program contributes to this mission by supporting projects that foster empirical research on societal, organizational, behavioral, group, and individual factors that affect, both positively and negatively, integrity in research with a focus on the identification of the root causes of research misconduct and driving factors for research integrity in compliance with 42 C.F.R. Part 93.
Link to Additional Information:	FY25 Ensuring Research Integrity – Program Development and Evaluation Program (PDE)
Grantor Contact Information:	If you have difficulty accessing the full announcement electronically, please contact: Grants.gov Contact Center Phone Number: 1-800-518-4726 Hours of operation are 24 hours a day, 7 days a week. The contact center is closed on federal holidays. Email:-

Version History

Version	Modification Description	Updated Date
	No Explanation	Jul 14, 2025
		Jul 03, 2025
		Jul 03, 2025
		Jul 03, 2025
	Revised dates and summary	Aug 01, 2024
	Revised dates and summary	Aug 01, 2024
	Revised dates and summary	Aug 01, 2024
		Aug 01, 2024

DISPLAYING: Synopsis 4

General Information

Document Type:	Grants Notice
Funding Opportunity Number:	IR-ORI-25-003
Funding Opportunity Title:	FY25 Ensuring Research Integrity – Program Development and Evaluation Program (PDE)
Opportunity Category:	Discretionary
Opportunity Category Explanation:	–
Funding Instrument Type:	Grant
Category of Funding Activity:	Science and Technology and other Research and Development
Category Explanation:	–
Expected Number of Awards:	2
Assistance Listings:	93.085 — Research on Research Integrity
Cost Sharing or Matching Requirement:	No
Version:	Synopsis 4
Posted Date:	Jul 03, 2025
Last Updated Date:	Jul 14, 2025
Original Closing Date for Applications:	Jul 30, 2025 No Explanation
Current Closing Date for Applications:	Jul 30, 2025 No Explanation
Archive Date:	Aug 29, 2025
Estimated Total Program Funding:	$500,000
Award Ceiling:	$250,000
Award Floor:	$150,000

Eligibility

Eligible Applicants:

Agency Name:	Office of the Assistant Secretary for Health
Description:	The Office of Research Integrity (ORI) anticipates the availability of funding to support projects for the development and implementation of innovative approaches and tools to promote research integrity and prevent misconduct. This includes creating interventions based on empirical evidence, including findings from ORI-funded research, and tools to identify at-risk individuals or laboratories. This opportunity supports the creation and evaluation of interventions and assessment tools aimed at promoting research integrity, while ensuring transparency, accountability, and ethical scientific practices that serve public health and societal well-being Projects may include all, or a number of the goals below:1) Development of educational resources toCreate novel online training modules incorporating interactive scenarios to teach principles of research integrity, ensuring that researchers are equipped with tools to navigate ethical dilemmas and resist external pressures that compromise scientific integrityDevelop engaging, in-person or classroom educational programs that promote the responsible conduct of research, prevent research misconduct, or encourages the reporting of suspected research misconduct, fostering a research culture that prioritizes public trust and accountability.Evaluate the effectiveness of the developed educational and training resources, to ensure alignment with the highest ethical standards in science and public health. 2) Creation of risk assessment tools to Design, develop, and test assessment tools for principal investigators, department chairs, or other research administrators to evaluate the risk for individuals, laboratories, or research programs – to engage in misconduct or detrimental research practicesDesign, develop, and test assessment tool that examines institutional research culture or practices that impact or lead to potential research misconduct.Evaluate the effectiveness of the development risk assessment tools, to strengthen the integrity of research institutions and ensure compliance with public health priorities.3) Implementation and Testing of Intervention Programs toCreate pilot interventions designed to improve data management and record-keeping in labs, with pre- and post-assessment of research integrity, ensuring research findings are transparent, reproducible, and free from manipulation.Implementation of mentorship and leadership training programs in research settings to foster a culture of ethical and responsible research.Evaluate the effectiveness of intervention programs to measure long-term impact, ensuring that scientific research upholds ethical principles that benefit public health.The recipient owns the copyright for materials developed under an award, and pursuant to 45 C.F.R. § 75.322(b), HHS reserves a royalty-free, nonexclusive, and irrevocable right to reproduce, publish, or otherwise use those materials for federal purposes, and to authorize others to do so. In addition, pursuant to 45 C.F.R. § 75.322(d), the federal government has the right to obtain, reproduce, publish, or otherwise use data produced under this award and has the right to authorize others to receive, reproduce, publish, or otherwise use such data for federal purposes.We expect to fund awards in 12-month budget periods for a total period of performance up to 24 months. Recipients must submit a non-competing continuation (NCC) application for each budget period after the first. Continuation funding is contingent upon the availability of funds, satisfactory progress of the project, appropriate stewardship of federal funds, and the best interests of the government. Funding for all approved budget periods after the first is generally the same as the initial award amount subject to any offset with funds unused in the previous budget period. Universities, hospitals, laboratories, other public or private institutions, and individuals are eligible to apply for an award under this opportunity. Eligible entities include faith-based organizations, community-based organizations, and American Indian/Alaska Native/Native American (AI/AN/NA) organizations. Eligible entities include foreign organizations and foreign components of domestic organizations, if the proposed activity provides a domestic benefit, such as promoting research integrity among PHS-funded institutions both within the U.S. and abroad.
Link to Additional Information:	–
Grantor Contact Information:	If you have difficulty accessing the full announcement electronically, please contact: – Email:Armineh.Ghazarian@hhs.gov

Agency Name:	Office of the Assistant Secretary for Health
Description:	The Office of Research Integrity (ORI) anticipates the availability of funding to support projects for the development and implementation of innovative approaches and tools to promote research integrity and prevent misconduct. This includes creating interventions based on empirical evidence, including findings from ORI-funded research, and tools to identify at-risk individuals or laboratories. This opportunity supports the creation and evaluation of interventions and assessment tools aimed at promoting research integrity, while ensuring transparency, accountability, and ethical scientific practices that serve public health and societal well-being Projects may include all, or a number of the goals below:1) Development of educational resources toCreate novel online training modules incorporating interactive scenarios to teach principles of research integrity, ensuring that researchers are equipped with tools to navigate ethical dilemmas and resist external pressures that compromise scientific integrityDevelop engaging, in-person or classroom educational programs that promote the responsible conduct of research, prevent research misconduct, or encourages the reporting of suspected research misconduct, fostering a research culture that prioritizes public trust and accountability.Evaluate the effectiveness of the developed educational and training resources, to ensure alignment with the highest ethical standards in science and public health. 2) Creation of risk assessment tools to Design, develop, and test assessment tools for principal investigators, department chairs, or other research administrators to evaluate the risk for individuals, laboratories, or research programs – to engage in misconduct or detrimental research practicesDesign, develop, and test assessment tool that examines institutional research culture or practices that impact or lead to potential research misconduct.Evaluate the effectiveness of the development risk assessment tools, to strengthen the integrity of research institutions and ensure compliance with public health priorities.3) Implementation and Testing of Intervention Programs toCreate pilot interventions designed to improve data management and record-keeping in labs, with pre- and post-assessment of research integrity, ensuring research findings are transparent, reproducible, and free from manipulation.Implementation of mentorship and leadership training programs in research settings to foster a culture of ethical and responsible research.Evaluate the effectiveness of intervention programs to measure long-term impact, ensuring that scientific research upholds ethical principles that benefit public health.The recipient owns the copyright for materials developed under an award, and pursuant to 45 C.F.R. § 75.322(b), HHS reserves a royalty-free, nonexclusive, and irrevocable right to reproduce, publish, or otherwise use those materials for federal purposes, and to authorize others to do so. In addition, pursuant to 45 C.F.R. § 75.322(d), the federal government has the right to obtain, reproduce, publish, or otherwise use data produced under this award and has the right to authorize others to receive, reproduce, publish, or otherwise use such data for federal purposes.We expect to fund awards in 12-month budget periods for a total period of performance up to 24 months. Recipients must submit a non-competing continuation (NCC) application for each budget period after the first. Continuation funding is contingent upon the availability of funds, satisfactory progress of the project, appropriate stewardship of federal funds, and the best interests of the government. Funding for all approved budget periods after the first is generally the same as the initial award amount subject to any offset with funds unused in the previous budget period. Universities, hospitals, laboratories, other public or private institutions, and individuals are eligible to apply for an award under this opportunity. Eligible entities include faith-based organizations, community-based organizations, and American Indian/Alaska Native/Native American (AI/AN/NA) organizations. Eligible entities include foreign organizations and foreign components of domestic organizations, if the proposed activity provides a domestic benefit, such as promoting research integrity among PHS-funded institutions both within the U.S. and abroad.
Link to Additional Information:	–
Grantor Contact Information:	If you have difficulty accessing the full announcement electronically, please contact: – Email:Armineh.Ghazarian@hhs.gov

Agency Name:	Office of the Assistant Secretary for Health
Description:	The Office of Research Integrity (ORI) anticipates the availability of funding to support projects for the development and implementation of innovative approaches and tools to promote research integrity and prevent misconduct. This includes creating interventions based on empirical evidence, including findings from ORI-funded research, and tools to identify at-risk individuals or laboratories. This opportunity supports the creation and evaluation of interventions and assessment tools aimed at promoting research integrity, while ensuring transparency, accountability, and ethical scientific practices that serve public health and societal well-being Projects may include all, or a number of the goals below:1) Development of educational resources toCreate novel online training modules incorporating interactive scenarios to teach principles of research integrity, ensuring that researchers are equipped with tools to navigate ethical dilemmas and resist external pressures that compromise scientific integrityDevelop engaging, in-person or classroom educational programs that promote the responsible conduct of research, prevent research misconduct, or encourages the reporting of suspected research misconduct, fostering a research culture that prioritizes public trust and accountability.Evaluate the effectiveness of the developed educational and training resources, to ensure alignment with the highest ethical standards in science and public health. 2) Creation of risk assessment tools to Design, develop, and test assessment tools for principal investigators, department chairs, or other research administrators to evaluate the risk for individuals, laboratories, or research programs – to engage in misconduct or detrimental research practicesDesign, develop, and test assessment tool that examines institutional research culture or practices that impact or lead to potential research misconduct.Evaluate the effectiveness of the development risk assessment tools, to strengthen the integrity of research institutions and ensure compliance with public health priorities.3) Implementation and Testing of Intervention Programs toCreate pilot interventions designed to improve data management and record-keeping in labs, with pre- and post-assessment of research integrity, ensuring research findings are transparent, reproducible, and free from manipulation.Implementation of mentorship and leadership training programs in research settings to foster a culture of ethical and responsible research.Evaluate the effectiveness of intervention programs to measure long-term impact, ensuring that scientific research upholds ethical principles that benefit public health.The recipient owns the copyright for materials developed under an award, and pursuant to 45 C.F.R. § 75.322(b), HHS reserves a royalty-free, nonexclusive, and irrevocable right to reproduce, publish, or otherwise use those materials for federal purposes, and to authorize others to do so. In addition, pursuant to 45 C.F.R. § 75.322(d), the federal government has the right to obtain, reproduce, publish, or otherwise use data produced under this award and has the right to authorize others to receive, reproduce, publish, or otherwise use such data for federal purposes.We expect to fund awards in 12-month budget periods for a total period of performance up to 24 months. Recipients must submit a non-competing continuation (NCC) application for each budget period after the first. Continuation funding is contingent upon the availability of funds, satisfactory progress of the project, appropriate stewardship of federal funds, and the best interests of the government. Funding for all approved budget periods after the first is generally the same as the initial award amount subject to any offset with funds unused in the previous budget period. Universities, hospitals, laboratories, other public or private institutions, and individuals are eligible to apply for an award under this opportunity. Eligible entities include faith-based organizations, community-based organizations, and American Indian/Alaska Native/Native American (AI/AN/NA) organizations. Eligible entities include foreign organizations and foreign components of domestic organizations, if the proposed activity provides a domestic benefit, such as promoting research integrity among PHS-funded institutions both within the U.S. and abroad.
Link to Additional Information:	–
Grantor Contact Information:	If you have difficulty accessing the full announcement electronically, please contact: – Email:Armineh.Ghazarian@hhs.gov

Agency Name:	Office of the Assistant Secretary for Health
Description:	The Office of Research Integrity (ORI) anticipates the availability of funding to support projects for the development and implementation of innovative approaches and tools to promote research integrity and prevent misconduct. This includes creating interventions based on empirical evidence, including findings from ORI-funded research, and tools to identify at-risk individuals or laboratories. This opportunity supports the creation and evaluation of interventions and assessment tools aimed at promoting research integrity. Projects may include all, or a number of the goals below:1) Development of educational resources toCreate novel online training modules incorporating interactive scenarios to teach principles of research integrityDevelop engaging, in-person or classroom educational programs that promote the responsible conduct of research, prevent research misconduct, or encourages the reporting of suspected research misconduct.Evaluate the effectiveness of the developed educational and training resources 2) Creation of risk assessment tools to Design, develop, and test assessment tools for principal investigators, department chairs, or other research administrators to evaluate the risk for individuals, laboratories, or research programs – to engage in misconduct or detrimental research practicesDesign, develop, and test assessment tool that examines institutional research culture or practices that impact or lead to potential research misconduct.Evaluate the effectiveness of the development risk assessment tool 3) Implementation and Testing of Intervention Programs toCreate pilot interventions designed to improve data management and record-keeping in labs, with pre- and post-assessment of research integrityImplementation of mentorship and leadership training programs in research settings to foster a culture of ethical and responsible research.Evaluate the effectiveness of intervention programs The recipient owns the copyright for materials developed under an award, and pursuant to 45 C.F.R. § 75.322(b), HHS reserves a royalty-free, nonexclusive, and irrevocable right to reproduce, publish, or otherwise use those materials for federal purposes, and to authorize others to do so. In addition, pursuant to 45 C.F.R. § 75.322(d), the federal government has the right to obtain, reproduce, publish, or otherwise use data produced under this award and has the right to authorize others to receive, reproduce, publish, or otherwise use such data for federal purposes.We expect to fund awards in 12-month budget periods for a total period of performance up to 24 months. Recipients must submit a non-competing continuation (NCC) application for each budget period after the first. Continuation funding is contingent upon the availability of funds, satisfactory progress of the project, appropriate stewardship of federal funds, and the best interests of the government. Funding for all approved budget periods after the first is generally the same as the initial award amount subject to any offset with funds unused in the previous budget period. Universities, hospitals, laboratories, other public or private institutions, and individuals are eligible to apply for an award under this opportunity. Eligible entities include faith-based organizations, community-based organizations, and American Indian/Alaska Native/Native American (AI/AN/NA) organizations. Eligible entities include foreign organizations and foreign components of domestic organizations, if the proposed activity provides a domestic benefit, such as promoting research integrity among PHS-funded institutions both within the U.S. and abroad.
Link to Additional Information:	–
Grantor Contact Information:	If you have difficulty accessing the full announcement electronically, please contact: – Email:Armineh.Ghazarian@hhs.gov

Office of Research Integrity (ORI) Grant: Enhancing Research Integrity and Preventing Misconduct

General Information

Eligibility

Additional Information

Version History

DISPLAYING: Synopsis 4

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DISPLAYING: Synopsis 3

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DISPLAYING: Synopsis 2

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DISPLAYING: Synopsis 1

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DISPLAYING: Forecast 4

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DISPLAYING: Forecast 3

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DISPLAYING: Forecast 2

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DISPLAYING: Forecast 1

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