The Office of Strategic Coordination, National Institutes of Health, is offering this U42 grant to fund institutions/organizations for knockout mouse production and cryopreservation. The grant’s purpose is to convert International Knockout Mouse Consortiums embryonic stem cell libraries into mice, perform quality control, and cooperatively send these mice to successful grantees for phenotyping. Additionally, recipients will cryopreserve germplasm from these mice and send aliquots to the KOMP repository. The overall objective is to generate crucial resources required by NIH-funded Mouse Phenotyping Centers, enabling them to produce functional information for every protein-coding gene in the mammalian genome. Up to $12.4 million per year is available, with 1-3 awards anticipated over a maximum of five years.
Opportunity ID: 57187
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-RM-10-013 |
| Funding Opportunity Title: | Knockout Mouse Production and Cryopreservation (U42) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Education Health Income Security and Social Services |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.121 — Oral Diseases and Disorders Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Sep 10, 2010 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Nov 10, 2010 |
| Current Closing Date for Applications: | Nov 10, 2010 |
| Archive Date: | Dec 11, 2010 |
| Estimated Total Program Funding: | $62,000,000 |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | State governments Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Others (see text field entitled “Additional Information on Eligibility” for clarification) Small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs) . |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | Purpose. This FOA issued by the Office of Strategic Coordination, National Institutes of Health, solicits grant applications from institutions/ organizations that propose to convert the International Knockout Mouse Consortiums knockout embryonic stem (ES) cell libraries (www.komp.org and www.eummcr.org), into mice, perform quality control (QC) on the imported materials and subsequent products, cooperatively send the mice to the successful grantees under RFA-RM-10-011 for phenotyping, and cryopreserve germplasm of those mice and send aliquots to the KOMP repository. The overall objective of this FOA is to generate the resources needed by NIH-funded Mouse Phenotyping Centers to produce functional information for each protein coding gene in the mammalian genome as described in RFA-RM-10-011. Mechanism of Support. This FOA will utilize the U42 award mechanism and runs in parallel with two additional FOAs that solicits applications under the U54 award mechanism (RFA-RM-10-012, RFA-RM-10-011). Funds Available and Anticipated Number of Awards. Up to $12.4 million in total costs per year for periods up to 5 years may be requested. It is anticipated that 1-3 awards will be made contingent upon receiving scientifically meritorious proposals. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-10-013.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
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