This grant is for advancing research into the molecular underpinnings of telomere status and associated biological pathways in response to environmental exposures. The funding opportunity aims to characterize how telomere maintenance modulates downstream biological pathways, potentially leading to cellular and organismal dysfunction. It specifically seeks to stimulate studies examining how environmental exposure effects at telomeric regions may potentiate the early onset of age-related diseases. Ultimately, this grant aims to identify key mechanistic insights into telomere dynamics, better dissecting how environmental exposures at this vulnerable site contribute to various diseases, including cancer, cardiovascular disease, and neurodegeneration.
Opportunity ID: 344147
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-ES-22-007 |
| Funding Opportunity Title: | Utilizing Telomere Status to Reveal Molecular Mechanisms Underlying Susceptibility and Resiliency in Response to Environmental Exposures (R01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Environment Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.113 — Environmental Health |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Oct 21, 2022 |
| Last Updated Date: | Oct 21, 2022 |
| Original Closing Date for Applications: | Feb 14, 2023 |
| Current Closing Date for Applications: | Feb 14, 2023 |
| Archive Date: | Mar 22, 2023 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Public housing authorities/Indian housing authorities City or township governments County governments For profit organizations other than small businesses Special district governments Small businesses Public and State controlled institutions of higher education Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Others (see text field entitled “Additional Information on Eligibility” for clarification) Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments Private institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this funding opportunity announcement (FOA) is to solicit applications that further examine and characterize molecular underpinnings surrounding telomere status and accompanying biological pathways in response to environmental insults. Specifically, the intent is to further stimulate the field on how general telomere maintenance modulates downstream biological pathway(s) leading to cellular and organismal dysfunction. It is anticipated that proposed studies examining exposure affects at telomeric regions can actually potentiate early onset of age-related diseases. This FOA ultimately seeks to identify key mechanistic insights into telomere dynamics and how this could better dissect the interplay between environmental exposures at this vulnerable site contribute to disease (e.g., cancer, CVD, and other age-related outcomes, such as neurodegeneration). |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-ES-22-007.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00277872 | Jan 14, 2023 | Feb 14, 2023 | View | |
| FORMS-G | Use for due dates on or before January 24, 2023 | PKG00277388 | Jan 14, 2023 | Jan 24, 2023 | View |
Package 1
Mandatory forms
344147 RR_SF424_5_0-5.0.pdf
344147 PHS398_CoverPageSupplement_5_0-5.0.pdf
344147 RR_OtherProjectInfo_1_4-1.4.pdf
344147 PerformanceSite_4_0-4.0.pdf
344147 RR_KeyPersonExpanded_4_0-4.0.pdf
344147 PHS398_ResearchPlan_5_0-5.0.pdf
344147 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
344147 RR_Budget_3_0-3.0.pdf
344147 RR_SubawardBudget30_3_0-3.0.pdf
344147 PHS398_ModularBudget_1_2-1.2.pdf
344147 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 2
Mandatory forms
344147 RR_SF424_5_0-5.0.pdf
344147 PHS398_CoverPageSupplement_5_0-5.0.pdf
344147 RR_OtherProjectInfo_1_4-1.4.pdf
344147 PerformanceSite_4_0-4.0.pdf
344147 RR_KeyPersonExpanded_4_0-4.0.pdf
344147 PHS398_ResearchPlan_4_0-4.0.pdf
344147 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
344147 RR_Budget_3_0-3.0.pdf
344147 RR_SubawardBudget30_3_0-3.0.pdf
344147 PHS398_ModularBudget_1_2-1.2.pdf
344147 PHS_AssignmentRequestForm_3_0-3.0.pdf
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