NIH HPAP-T2D Program: Study of Pancreatic Tissues for Type-2 Diabetes with $2M Award Ceiling
The National Institutes of Health (NIH) is soliciting cooperative agreement applications for the continuation of the Human Pancreas Analysis Program for Type-2 Diabetes (HPAP-T2D). This program supports the study of pancreatic tissues from individuals with Type 2 Diabetes (T2D) and related metabolic disorders. The objective is to intensively characterize these tissues and share the resulting data through the existing PANC DB open-access resource database. Small businesses are among the eligible applicants, and the award ceiling is $2,000,000.
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DK-25-002 |
| Funding Opportunity Title: | Single Source for continuation of the Human Pancreas Analysis Program for Type-2 Diabetes (HPAP-T2D) (U01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Food and Nutrition Health |
| Category Explanation: | |
| Expected Number of Awards: | |
| CFDA Number(s): | 93.847 — Diabetes, Digestive, and Kidney Diseases Extramural Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Oct 24, 2023 |
| Last Updated Date: | Oct 24, 2023 |
| Original Closing Date for Applications: | Feb 28, 2024 |
| Current Closing Date for Applications: | Feb 28, 2024 |
| Archive Date: | Apr 04, 2024 |
| Estimated Total Program Funding: | |
| Award Ceiling: | $2,000,000 |
| Award Floor: | $ |
Eligibility
| Eligible Applicants: | Small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Notice of Funding Opportunity (NOFO) invites cooperative agreement applications to expand the operational scope of the existing Human Pancreas Analysis Program (HPAP) to the study of pancreata recovered from tissue donors with Type 2 Diabetes (T2D) and related metabolic disorders. This NOFO will support one team of investigators with combined expertise in human pancreas physiology and pathophysiology; collection, processing and multimodal analysis of human pancreatic tissues; and biological database building, curation and management, that will be tasked to: 1) identify, collect and intensively characterize primary pancreatic tissues from patients with T2D and related forms of islet dysfunction, as well as age-matched controls; and 2) analyze, organize and share the data resulting from the study of these tissues through use and expansion of the existing PANC DB open-access resource database. HPAP is a component of the Human Islet Research Network (HIRN), created in 2014 to support innovative and collaborative translational research to understand how human beta cells are lost in Type 1 Diabetes (T1D), and to find innovative strategies to protect and replace functional human beta cell mass. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-DK-25-002.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact: NIH Grants Information
grantsinfo@nih.gov |