This Funding Opportunity Announcement invites applications to establish the Data Analysis Center (DAC) for the Somatic Mosaicism across Human Tissues (SMaHT) Network. This grant is for the critical role of managing and leveraging vast genomic data to advance the understanding of somatic mosaicism. The SMaHT Network aims to uncover new biological insights and disease mechanisms driven by genomic variations in somatic tissues. The chosen DAC will be responsible for comprehensive data management, including ingestion, uniform processing, standardized annotation, and secure archiving. Furthermore, the DAC will develop and deploy innovative computational methods and bioinformatics tools as an accessible data workbench. Key functions also include building a robust data portal, featuring the SMaHT Variant Catalog and a variant browser, and ensuring harmonization of SMaHT resources with related scientific programs. This initiative is crucial for propelling discoveries in genomic research.
Opportunity ID: 338290
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-RM-22-010 |
| Funding Opportunity Title: | Somatic Mosaicism across Human Tissues (SMaHT) Program: Data Analysis Center (UM1 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.310 — Trans-NIH Research Support |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Feb 23, 2022 |
| Last Updated Date: | Feb 23, 2022 |
| Original Closing Date for Applications: | Jul 08, 2022 |
| Current Closing Date for Applications: | Jul 08, 2022 |
| Archive Date: | Aug 13, 2022 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Independent school districts Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Special district governments County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Small businesses State governments City or township governments Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Native American tribal governments (Federally recognized) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) invites applications to establish the Data Analysis Center (DAC) for the Somatic Mosaicism across Human Tissues (SMaHT) Network. ?The purpose of the SMaHT Network is to enable discovery of new biology and disease mechanisms mediated by genomic variation in somatic tissues. The Data Analysis Center will be responsible for the following areas: 1. Managing all data on behalf of the Network, including ingestion, uniform processing, and standardized annotation, and archiving of data; 2. Developing new computational methods and bioinformatics tools and deploying them as part of an accessible data workbench; 3. Building a data portal for the Network, including the SMaHT Variant Catalog and variant browser, and 4. Harmonizing SMaHT resources with related programs. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-22-010.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
OERWebmaster03@od.nih.gov Email:OERWebmaster03@od.nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 338290 Full Announcement-RFA-RM-22-010 -> RFA-RM-22-010-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH OER Webmaster OERWebmaster03@od.nih.gov Email: OERWebmaster03@od.nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-G | Use for due dates on or after January 25, 2022 | PKG00272184 | Jun 08, 2022 | Jul 08, 2022 | View |
Package 1
Mandatory forms
338290 RR_SF424_5_0-5.0.pdf
338290 PHS398_CoverPageSupplement_5_0-5.0.pdf
338290 RR_OtherProjectInfo_1_4-1.4.pdf
338290 PerformanceSite_4_0-4.0.pdf
338290 RR_KeyPersonExpanded_4_0-4.0.pdf
338290 RR_Budget_3_0-3.0.pdf
338290 PHS398_ResearchPlan_4_0-4.0.pdf
338290 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
338290 RR_SubawardBudget30_3_0-3.0.pdf
338290 PHS_AssignmentRequestForm_3_0-3.0.pdf
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