This grant, offered by the Alzheimer’s Clinical Trials Consortium (ACTC), is for the purpose of supporting the development and implementation of multi-site clinical trials. Specifically, it targets Phase Ib to III trials evaluating promising pharmacological and non-pharmacological interventions. The goal is to prevent, delay, or treat the symptoms of Alzheimer’s disease (AD) and other age-related dementias. Applicants are expected to leverage the existing ACTC trial coordination and management infrastructure, ensuring efficient and collaborative research efforts. This funding opportunity seeks to advance innovative treatments and improve patient outcomes by facilitating rigorous, large-scale studies in the field of neurodegenerative diseases. The initiative underscores a commitment to combating the challenges posed by AD and related conditions through robust clinical research.
Opportunity ID: 355231
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AG-25-010 |
| Funding Opportunity Title: | Alzheimer’s Clinical Trials Consortium (ACTC) Clinical Trials (R01 Clinical Trial Required) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.866 — Aging Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jul 01, 2024 |
| Last Updated Date: | Jul 01, 2024 |
| Original Closing Date for Applications: | Oct 17, 2024 |
| Current Closing Date for Applications: | Oct 17, 2024 |
| Archive Date: | Nov 22, 2024 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | State governments Independent school districts Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled “Additional Information on Eligibility” for clarification) Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Special district governments For profit organizations other than small businesses Private institutions of higher education Small businesses Public housing authorities/Indian housing authorities County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Notice of Funding Opportunity (NOFO) invites applications to develop and implement multi-site Phase Ib to III clinical trials of promising pharmacological and non-pharmacological interventions that may prevent, delay, or treat the symptoms of Alzheimer’s disease (AD) and other age-related dementias using the Alzheimer’s disease Clinical Trials Consortium (ACTC) trial coordination and management infrastructure. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-AG-25-010.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 355231 Full Announcement-RFA-AG-25-010 -> RFA-AG-25-010-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00287246 | Sep 16, 2024 | Oct 17, 2024 | View |
Package 1
Mandatory forms
355231 RR_SF424_5_0-5.0.pdf
355231 PHS398_CoverPageSupplement_5_0-5.0.pdf
355231 RR_OtherProjectInfo_1_4-1.4.pdf
355231 PerformanceSite_4_0-4.0.pdf
355231 RR_KeyPersonExpanded_4_0-4.0.pdf
355231 PHS398_ResearchPlan_5_0-5.0.pdf
355231 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
355231 RR_Budget_3_0-3.0.pdf
355231 RR_SubawardBudget30_3_0-3.0.pdf
355231 PHS398_ModularBudget_1_2-1.2.pdf
355231 PHS_AssignmentRequestForm_3_0-3.0.pdf
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