The BRAIN Initiative is offering a grant designed to foster the development and rigorous validation of innovative tools for neuroscience research. This grant aims to facilitate the detailed analysis of complex neural circuits and deepen understanding of cellular interactions that underpin brain function. Proposed tools and technologies should specifically target cell-type and/or circuit-level processes with enhanced precision and sensitivity, surpassing existing methods. Applications are encouraged for novel genetic and non-genetic tools capable of delivering genes, proteins, or chemicals to specific cells. A strong emphasis is placed on comprehensive validation plans and the potential for these tools to be utilized across multiple species or model organisms, significantly advancing current neurotechnological capabilities.
Opportunity ID: 348011
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-MH-23-290 |
| Funding Opportunity Title: | BRAIN Initiative: Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain (R01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health Income Security and Social Services |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.173 — Research Related to Deafness and Communication Disorders |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | May 08, 2023 |
| Last Updated Date: | May 08, 2023 |
| Original Closing Date for Applications: | Jun 07, 2023 |
| Current Closing Date for Applications: | Jun 07, 2023 |
| Archive Date: | Jul 13, 2023 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | County governments City or township governments Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) Special district governments Public and State controlled institutions of higher education Small businesses Public housing authorities/Indian housing authorities Others (see text field entitled “Additional Information on Eligibility” for clarification) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education For profit organizations other than small businesses Independent school districts State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This is a reissue of RFA-MH-21-175 to comply with DMSP policy. The purpose of this Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is to encourage applications that will develop and validate novel tools to facilitate the detailed analysis of complex circuits and provide insights into cellular interactions that underlie brain function. The new tools and technologies should inform and/or exploit cell-type and/or circuit-level specificity. Plans for validating the utility of the tool/technology will be an essential feature of a successful application. The development of new genetic and non-genetic tools for delivering genes, proteins and chemicals to cells of interest or approaches that are expected to target specific cell types and/or circuits in the nervous system with greater precision and sensitivity than currently established methods are encouraged. Tools that can be used in a number of species/model organisms rather than those restricted to a single species are highly desired. Applications that provide approaches that break through existing technical barriers to substantially improve current capabilities are highly encouraged. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-MH-23-290.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00281570 | May 08, 2023 | Jun 07, 2023 | View |
Package 1
Mandatory forms
348011 RR_SF424_5_0-5.0.pdf
348011 PHS398_CoverPageSupplement_5_0-5.0.pdf
348011 RR_OtherProjectInfo_1_4-1.4.pdf
348011 PerformanceSite_4_0-4.0.pdf
348011 RR_KeyPersonExpanded_4_0-4.0.pdf
348011 PHS398_ResearchPlan_5_0-5.0.pdf
348011 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
348011 RR_Budget_3_0-3.0.pdf
348011 RR_SubawardBudget30_3_0-3.0.pdf
348011 PHS398_ModularBudget_1_2-1.2.pdf
348011 PHS_AssignmentRequestForm_3_0-3.0.pdf
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