This grant is for supporting collaborative and integrated research programs focused on HIV prevention and cure. It aims to identify the correlates and mechanisms of protection for preventive vaccines, and utilize vaccines or other immune modalities to advance cure research. Funding will support preclinical studies using nonhuman primate (NHP) models to investigate how efficacious AIDS vaccines protect against initial infection or establishment of systemic infection. The research will also incorporate various immune interventions into cure strategies for SIV or SHIV-infected NHPs, with the goal of eliminating viral reservoirs or establishing elite control of virus replication. Findings from these studies are intended to significantly improve HIV vaccines and cure strategies, paving the way for future evaluation in human clinical trials.
Opportunity ID: 333401
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AI-21-039 |
| Funding Opportunity Title: | Consortium for Innovative HIV/AIDS Vaccine and Cure Research (UM1 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.855 — Allergy and Infectious Diseases Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | May 07, 2021 |
| Last Updated Date: | May 07, 2021 |
| Original Closing Date for Applications: | Aug 04, 2021 |
| Current Closing Date for Applications: | Aug 04, 2021 |
| Archive Date: | Sep 09, 2021 |
| Estimated Total Program Funding: | $6,000,000 |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Public housing authorities/Indian housing authorities Private institutions of higher education Independent school districts Special district governments Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments For profit organizations other than small businesses Others (see text field entitled “Additional Information on Eligibility” for clarification) Native American tribal governments (Federally recognized) Small businesses Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education County governments State governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this funding opportunity announcement (FOA) is to support consortia to conduct research toward the prevention and cure of HIV. The Consortium for Innovative HIV Vaccine and Cure Research will establish a collaborative and integrated research program built around two areas of scientific focus: identification of the correlates and the mechanism(s) of protection of preventive vaccine(s) and the use of vaccines or other immune modalities in advancing cure research. Preclinical studies in nonhuman primate (NHP) models will be supported to investigate the mechanism(s), by which efficacious AIDS vaccines protect NHPs from initial infection or establishment of systemic infection, and will incorporate vaccines or other immune interventions into cure strategies in SIV or SHIV-infected NHPs with the objective of eliminating virus reservoirs or establishing elite control of virus replication. Research findings can be applied to improve HIV vaccines and cure strategies and further advancement toward evaluation in human clinical trials. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-AI-21-039.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-F | Use for due dates on or after May 25, 2020 | PKG00266993 | Jul 06, 2021 | Aug 04, 2021 | View |
Package 1
Mandatory forms
333401 RR_SF424_2_0-2.0.pdf
333401 PHS398_CoverPageSupplement_5_0-5.0.pdf
333401 RR_OtherProjectInfo_1_4-1.4.pdf
333401 PerformanceSite_2_0-2.0.pdf
333401 RR_KeyPersonExpanded_2_0-2.0.pdf
333401 RR_Budget_1_4-1.4.pdf
333401 PHS398_ResearchPlan_4_0-4.0.pdf
333401 PHSHumanSubjectsAndClinicalTrialsInfo_2_0-2.0.pdf
Optional forms
333401 RR_SubawardBudget30_1_4-1.4.pdf
333401 PHS_AssignmentRequestForm_3_0-3.0.pdf
Share This Post, Choose Your Platform!
About the Author: osnqt
