This grant, offered by a major health department, is specifically designed to support extensive research projects aimed at combating the growing threat of antibiotic-resistant bacteria (CARB). Recognizing the urgent global health challenge posed by drug-resistant infections, this funding opportunity seeks innovative, large-scale research (R01 level) to develop novel strategies, therapies, and diagnostics. Projects should contribute significantly to understanding resistance mechanisms, discovering new antimicrobial agents, or developing alternative approaches to prevent and treat resistant infections. The initiative emphasizes high-impact investigations that can accelerate progress in overcoming antimicrobial resistance, safeguarding public health against evolving bacterial threats.
Opportunity ID: 334655
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PA-22-047 |
| Funding Opportunity Title: | Large Research Projects for Combating Antibiotic-Resistant Bacteria (CARB) (R01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.226 — Research on Healthcare Costs, Quality and Outcomes |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 4 |
| Posted Date: | Oct 21, 2021 |
| Last Updated Date: | Mar 07, 2023 |
| Original Closing Date for Applications: | Oct 30, 2026 |
| Current Closing Date for Applications: | Oct 30, 2026 |
| Archive Date: | Dec 05, 2026 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education County governments State governments Public and State controlled institutions of higher education Private institutions of higher education Special district governments Independent school districts Public housing authorities/Indian housing authorities City or township governments Native American tribal governments (Federally recognized) Others (see text field entitled “Additional Information on Eligibility” for clarification) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. |
Additional Information
| Agency Name: | Agency for Health Care Research and Quality |
| Description: |
This Funding Opportunity Announcement (FOA) invites applications for grant funding to conduct Large Research Projects (R01) focused on Combating Antibiotic-Resistant Bacteria (CARB) . |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PA-22-047.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
Agency for Healthcare Research and Quality
Receipt and Referral Officer Please be sure to reference the opportunity number in your email. Email:Grant_Queries@ahrq.hhs.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
| updated grantor | Mar 07, 2023 | |
| updated grantor | Oct 21, 2021 | |
| updated eligibility criteria and grantor contact spacing | Oct 21, 2021 | |
| Oct 21, 2021 |
DISPLAYING: Synopsis 4
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PA-22-047 |
| Funding Opportunity Title: | Large Research Projects for Combating Antibiotic-Resistant Bacteria (CARB) (R01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.226 — Research on Healthcare Costs, Quality and Outcomes |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 4 |
| Posted Date: | Oct 21, 2021 |
| Last Updated Date: | Mar 07, 2023 |
| Original Closing Date for Applications: | Oct 30, 2026 |
| Current Closing Date for Applications: | Oct 30, 2026 |
| Archive Date: | Dec 05, 2026 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education County governments State governments Public and State controlled institutions of higher education Private institutions of higher education Special district governments Independent school districts Public housing authorities/Indian housing authorities City or township governments Native American tribal governments (Federally recognized) Others (see text field entitled “Additional Information on Eligibility” for clarification) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. |
Additional Information
| Agency Name: | Agency for Health Care Research and Quality |
| Description: |
This Funding Opportunity Announcement (FOA) invites applications for grant funding to conduct Large Research Projects (R01) focused on Combating Antibiotic-Resistant Bacteria (CARB) . |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PA-22-047.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
Agency for Healthcare Research and Quality
Receipt and Referral Officer Please be sure to reference the opportunity number in your email. Email:Grant_Queries@ahrq.hhs.gov |
DISPLAYING: Synopsis 3
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PA-22-047 |
| Funding Opportunity Title: | Large Research Projects for Combating Antibiotic-Resistant Bacteria (CARB) (R01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.226 — Research on Healthcare Costs, Quality and Outcomes |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 3 |
| Posted Date: | Oct 21, 2021 |
| Last Updated Date: | Jan 20, 2023 |
| Original Closing Date for Applications: | – |
| Current Closing Date for Applications: | Oct 30, 2026 |
| Archive Date: | Dec 05, 2026 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | State governments Private institutions of higher education County governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled “Additional Information on Eligibility” for clarification) Independent school districts Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Native American tribal governments (Federally recognized) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. |
Additional Information
| Agency Name: | Agency for Health Care Research and Quality |
| Description: |
This Funding Opportunity Announcement (FOA) invites applications for grant funding to conduct Large Research Projects (R01) focused on Combating Antibiotic-Resistant Bacteria (CARB) . |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PA-22-047.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
Agency for Healthcare Research and Quality
Receipt and Referral Officer Email: Grant_Queries@ahrq.hhs.gov Please be sure to reference the opportunity number in your email. Email:Grant_Queries@ahrq.hhs.gov |
DISPLAYING: Synopsis 2
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PA-22-047 |
| Funding Opportunity Title: | Large Research Projects for Combating Antibiotic-Resistant Bacteria (CARB) (R01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.226 — Research on Healthcare Costs, Quality and Outcomes |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 2 |
| Posted Date: | Oct 21, 2021 |
| Last Updated Date: | Jan 20, 2023 |
| Original Closing Date for Applications: | – |
| Current Closing Date for Applications: | Oct 30, 2026 |
| Archive Date: | Dec 05, 2026 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | State governments Private institutions of higher education County governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled “Additional Information on Eligibility” for clarification) Independent school districts Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Native American tribal governments (Federally recognized) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. |
Additional Information
| Agency Name: | Agency for Health Care Research and Quality |
| Description: |
This Funding Opportunity Announcement (FOA) invites applications for grant funding to conduct Large Research Projects (R01) focused on Combating Antibiotic-Resistant Bacteria (CARB) . |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PA-22-047.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
Kathryn Marron, Ph.D. Receipt and Referral Officer Agency for Healthcare Research and Quality, HHS Office: (301) 427-1554 Email: Kathryn.Marron@ahrq.hhs.gov
Kathryn.Marron@ahrq.hhs.gov Email:Kathryn.Marron@ahrq.hhs.gov |
DISPLAYING: Synopsis 1
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PA-22-047 |
| Funding Opportunity Title: | Large Research Projects for Combating Antibiotic-Resistant Bacteria (CARB) (R01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.226 — Research on Healthcare Costs, Quality and Outcomes |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Oct 21, 2021 |
| Last Updated Date: | Oct 21, 2021 |
| Original Closing Date for Applications: | – |
| Current Closing Date for Applications: | Oct 30, 2026 |
| Archive Date: | Dec 05, 2026 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | State governments Private institutions of higher education County governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Public housing authorities/Indian housing authorities For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments) Small businesses Others (see text field entitled “Additional Information on Eligibility” for clarification) Independent school districts Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Native American tribal governments (Federally recognized) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. |
Additional Information
| Agency Name: | Agency for Health Care Research and Quality |
| Description: | This Funding Opportunity Announcement (FOA) invites applications for grant funding to conduct Large Research Projects (R01) focused on Combating Antibiotic-Resistant Bacteria (CARB) . |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PA-22-047.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
Kathryn Marron, Ph.D. Receipt and Referral Officer Agency for Healthcare Research and Quality, HHS Office: (301) 427-1554 Email: Kathryn.Marron@ahrq.hhs.gov
Kathryn.Marron@ahrq.hhs.gov Email:Kathryn.Marron@ahrq.hhs.gov |
Related Documents
Folder 334655 Full Announcement-PA-22-047 -> PA-22-047-Full-Announcement.pdf
Packages
| Agency Contact Information: | Agency for Healthcare Research and Quality Receipt and Referral Officer Please be sure to reference the opportunity number in your email. Email: Grant_Queries@ahrq.hhs.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-F | Use for due dates on or before January 24, 2022 | PKG00269450 | Nov 01, 2021 | Jan 24, 2022 | View | |
| FORMS-G | Use for due dates on or before January 24, 2023 | PKG00270875 | Dec 15, 2021 | Jan 24, 2023 | View | |
| FORMS-H | Use for due dates on or before January 24, 2025 | PKG00278796 | Dec 05, 2022 | Jan 24, 2025 | View | |
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00289423 | Dec 04, 2024 | Oct 30, 2026 | View |
Package 1
Mandatory forms
334655 RR_SF424_5_0-5.0.pdf
334655 PHS398_CoverPageSupplement_5_0-5.0.pdf
334655 RR_OtherProjectInfo_1_4-1.4.pdf
334655 PerformanceSite_4_0-4.0.pdf
334655 RR_KeyPersonExpanded_4_0-4.0.pdf
334655 PHS398_ResearchPlan_5_0-5.0.pdf
334655 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
334655 RR_Budget_3_0-3.0.pdf
334655 RR_SubawardBudget30_3_0-3.0.pdf
334655 PHS398_ModularBudget_1_2-1.2.pdf
334655 PHS_AssignmentRequestForm_4_0-4.0.pdf
Package 2
Mandatory forms
334655 RR_SF424_2_0-2.0.pdf
334655 PHS398_CoverPageSupplement_5_0-5.0.pdf
334655 RR_OtherProjectInfo_1_4-1.4.pdf
334655 PerformanceSite_2_0-2.0.pdf
334655 RR_KeyPersonExpanded_2_0-2.0.pdf
334655 PHS398_ResearchPlan_4_0-4.0.pdf
334655 PHSHumanSubjectsAndClinicalTrialsInfo_2_0-2.0.pdf
Optional forms
334655 RR_Budget_1_4-1.4.pdf
334655 RR_SubawardBudget30_1_4-1.4.pdf
334655 PHS398_ModularBudget_1_2-1.2.pdf
334655 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 3
Mandatory forms
334655 RR_SF424_5_0-5.0.pdf
334655 PHS398_CoverPageSupplement_5_0-5.0.pdf
334655 RR_OtherProjectInfo_1_4-1.4.pdf
334655 PerformanceSite_4_0-4.0.pdf
334655 RR_KeyPersonExpanded_4_0-4.0.pdf
334655 PHS398_ResearchPlan_4_0-4.0.pdf
334655 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
334655 RR_Budget_3_0-3.0.pdf
334655 RR_SubawardBudget30_3_0-3.0.pdf
334655 PHS398_ModularBudget_1_2-1.2.pdf
334655 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 4
Mandatory forms
334655 RR_SF424_5_0-5.0.pdf
334655 PHS398_CoverPageSupplement_5_0-5.0.pdf
334655 RR_OtherProjectInfo_1_4-1.4.pdf
334655 PerformanceSite_4_0-4.0.pdf
334655 RR_KeyPersonExpanded_4_0-4.0.pdf
334655 PHS398_ResearchPlan_5_0-5.0.pdf
334655 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
334655 RR_Budget_3_0-3.0.pdf
334655 RR_SubawardBudget30_3_0-3.0.pdf
334655 PHS398_ModularBudget_1_2-1.2.pdf
334655 PHS_AssignmentRequestForm_3_0-3.0.pdf
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