This grant is for establishing specialized Centers aimed at accelerating the translational use of Microphysiological Systems (MPS) in drug development. Its core purpose is to facilitate the regulatory acceptance and industrial adoption of MPS, ensuring they are fit-for-purpose for industry needs and designed to meet regulatory approval expectations. These Centers will focus on developing MPS as vital drug development tools (DDTs) for both human pharmacological and biological products. Once qualified, these MPS-based DDTs will be made publicly and commercially available, effectively addressing unmet needs in drug development and fostering innovation in pharmaceutical research.
Opportunity ID: 345135
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-TR-23-001 |
| Funding Opportunity Title: | Translational Centers for Microphysiological Systems (TraCe MPS) (U2C Clinical Trials Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.350 — National Center for Advancing Translational Sciences |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Dec 27, 2022 |
| Last Updated Date: | Dec 27, 2022 |
| Original Closing Date for Applications: | Mar 27, 2023 |
| Current Closing Date for Applications: | Mar 27, 2023 |
| Archive Date: | May 02, 2023 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Private institutions of higher education City or township governments County governments Public and State controlled institutions of higher education Special district governments State governments Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Native American tribal governments (Federally recognized) Small businesses Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) For profit organizations other than small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this funding opportunity announcement (FOA) is to establish Centers to support research that will accelerate the translational use of Microphysiological Systems (MPS) in drug development through regulatory acceptance and adoption for industrial use, by establishing MPS that are fit-for-purpose for industry needs and have specific defined contexts of use (CoUs) and will be developed with consideration of applicable expectations to achieve regulatory approval. For this FOA, the term drugs refers to both human pharmacological and biological products unless otherwise specified. These Centers will further the development of MPS as drug development tools (DDTs) that, once qualified, will be made publicly and commercially available to fill unmet needs in drug development. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-TR-23-001.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 345135 Full Announcement-RFA-TR-23-001 -> RFA-TR-23-001-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00279048 | Feb 27, 2023 | Mar 27, 2023 | View |
Package 1
Mandatory forms
345135 RR_SF424_5_0-5.0.pdf
345135 PHS398_CoverPageSupplement_5_0-5.0.pdf
345135 RR_OtherProjectInfo_1_4-1.4.pdf
345135 PerformanceSite_4_0-4.0.pdf
345135 RR_KeyPersonExpanded_4_0-4.0.pdf
345135 PHS398_ResearchPlan_5_0-5.0.pdf
345135 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
345135 PHS_Additional_IndirectCosts_2_0-2.0.pdf
345135 PHS_AssignmentRequestForm_3_0-3.0.pdf
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