This HEAL Initiative grant is designed to advance our understanding of pain and enhance the research landscape. It aims to support R15-eligible Principal Investigators in conducting rigorous basic and mechanistic pain research projects. A core purpose of this grant is to promote integrated, interdisciplinary research partnerships among investigators from various U.S. domestic institutions. Furthermore, it seeks to significantly enhance the pain research environment at R15-eligible institutions by actively engaging health professional trainees, undergraduate, and/or graduate students in the proposed research projects. This initiative supports comprehensive efforts to deepen our knowledge of pain mechanisms and foster collaborative scientific discovery.
Opportunity ID: 356298
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AT-25-001 |
| Funding Opportunity Title: | HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health Income Security and Social Services |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.121 — Oral Diseases and Disorders Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 3 |
| Posted Date: | Sep 03, 2024 |
| Last Updated Date: | Jan 08, 2025 |
| Original Closing Date for Applications: | Nov 23, 2026 |
| Current Closing Date for Applications: | Jan 07, 2025 |
| Archive Date: | Feb 06, 2025 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $375,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Public and State controlled institutions of higher education Private institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs) ; See Funding Announcement for Eligibility criteriaNon-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: |
The purpose of this initiative is to: (1) support the efforts by R15-eligible Principal Investigators (PIs) to conduct rigorous basic and/or mechanistic pain research projects; (2) promote integrated, interdisciplinary research partnerships between R15-eligible PIs and additional investigators from U.S. domestic institutions, and (3) enhance the pain research environment at the R15-eligible institution for health professional trainees or undergraduate and/or graduate students by actively engaging them in the proposed pain research projects. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-AT-25-001.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
| Update close date per reissued NOFO RFA-AT-25-003. | Jan 08, 2025 | |
| Update ALN/CFDA per issuance of NOT-DE-25-040. | Sep 03, 2024 | |
| Sep 03, 2024 |
DISPLAYING: Synopsis 3
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AT-25-001 |
| Funding Opportunity Title: | HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health Income Security and Social Services |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.121 — Oral Diseases and Disorders Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 3 |
| Posted Date: | Sep 03, 2024 |
| Last Updated Date: | Jan 08, 2025 |
| Original Closing Date for Applications: | Nov 23, 2026 |
| Current Closing Date for Applications: | Jan 07, 2025 |
| Archive Date: | Feb 06, 2025 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $375,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Public and State controlled institutions of higher education Private institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs) ; See Funding Announcement for Eligibility criteriaNon-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: |
The purpose of this initiative is to: (1) support the efforts by R15-eligible Principal Investigators (PIs) to conduct rigorous basic and/or mechanistic pain research projects; (2) promote integrated, interdisciplinary research partnerships between R15-eligible PIs and additional investigators from U.S. domestic institutions, and (3) enhance the pain research environment at the R15-eligible institution for health professional trainees or undergraduate and/or graduate students by actively engaging them in the proposed pain research projects. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-AT-25-001.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
DISPLAYING: Synopsis 2
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AT-25-001 |
| Funding Opportunity Title: | HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health Income Security and Social Services |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.121 — Oral Diseases and Disorders Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 2 |
| Posted Date: | Sep 03, 2024 |
| Last Updated Date: | Oct 02, 2024 |
| Original Closing Date for Applications: | – |
| Current Closing Date for Applications: | Nov 23, 2026 |
| Archive Date: | Dec 29, 2026 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $375,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Others (see text field entitled “Additional Information on Eligibility” for clarification) Private institutions of higher education Public and State controlled institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs) ; See Funding Announcement for Eligibility criteriaNon-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this initiative is to: (1) support the efforts by R15-eligible Principal Investigators (PIs) to conduct rigorous basic and/or mechanistic pain research projects; (2) promote integrated, interdisciplinary research partnerships between R15-eligible PIs and additional investigators from U.S. domestic institutions, and (3) enhance the pain research environment at the R15-eligible institution for health professional trainees or undergraduate and/or graduate students by actively engaging them in the proposed pain research projects. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-AT-25-001.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
DISPLAYING: Synopsis 1
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AT-25-001 |
| Funding Opportunity Title: | HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health Income Security and Social Services |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.213 — Research and Training in Complementary and Integrative Health |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Sep 03, 2024 |
| Last Updated Date: | Sep 03, 2024 |
| Original Closing Date for Applications: | – |
| Current Closing Date for Applications: | Nov 23, 2026 |
| Archive Date: | Dec 29, 2026 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $375,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Others (see text field entitled “Additional Information on Eligibility” for clarification) Private institutions of higher education Public and State controlled institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs) ; See Funding Announcement for Eligibility criteria Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this initiative is to: (1) support the efforts by R15-eligible Principal Investigators (PIs) to conduct rigorous basic and/or mechanistic pain research projects; (2) promote integrated, interdisciplinary research partnerships between R15-eligible PIs and additional investigators from U.S. domestic institutions, and (3) enhance the pain research environment at the R15-eligible institution for health professional trainees or undergraduate and/or graduate students by actively engaging them in the proposed pain research projects. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-AT-25-001.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Related Documents
Folder 356298 Full Announcement-RFA-AT-25-001 -> RFA-AT-25-001-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or before January 24, 2025 | PKG00287818 | Oct 18, 2024 | Jan 09, 2025 | View | |
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00289109 | Nov 26, 2024 | Jan 09, 2025 | View |
Package 1
Mandatory forms
356298 RR_SF424_5_0-5.0.pdf
356298 PHS398_CoverPageSupplement_5_0-5.0.pdf
356298 RR_OtherProjectInfo_1_4-1.4.pdf
356298 PerformanceSite_4_0-4.0.pdf
356298 RR_KeyPersonExpanded_4_0-4.0.pdf
356298 PHS398_ResearchPlan_5_0-5.0.pdf
356298 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
356298 RR_Budget_3_0-3.0.pdf
356298 RR_SubawardBudget30_3_0-3.0.pdf
356298 PHS398_ModularBudget_1_2-1.2.pdf
356298 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 2
Mandatory forms
356298 RR_SF424_5_0-5.0.pdf
356298 PHS398_CoverPageSupplement_5_0-5.0.pdf
356298 RR_OtherProjectInfo_1_4-1.4.pdf
356298 PerformanceSite_4_0-4.0.pdf
356298 RR_KeyPersonExpanded_4_0-4.0.pdf
356298 PHS398_ResearchPlan_5_0-5.0.pdf
356298 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
356298 RR_Budget_3_0-3.0.pdf
356298 RR_SubawardBudget30_3_0-3.0.pdf
356298 PHS398_ModularBudget_1_2-1.2.pdf
356298 PHS_AssignmentRequestForm_4_0-4.0.pdf
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