This grant supports the establishment of a Data Management and Coordinating Center (DMCC) for the Liver Cancer Consortium, an initiative designed to advance translational research in early liver cancer detection. The Consortium aims to improve surveillance in high-risk populations, increase early detection rates, and better stratify patient risk. The DMCC will provide essential support to Translational Research Centers (TRCs) by coordinating trans-Consortium activities. Its responsibilities include administrative and logistical coordination, supporting collaborative research studies (including protocol development, data processing, and statistical analysis), and managing an integrated database for all research and biospecimen data. This center requires multidisciplinary expertise in liver cancer, biostatistics, bioinformatics, and robust IT infrastructure to achieve its critical data management goals.
Opportunity ID: 343133
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-CA-22-032 |
| Funding Opportunity Title: | Consortium on Translational Research in Early Detection of Liver Cancer: Data Management and Coordinating Center (U24 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | 1 |
| Assistance Listings: | 93.394 — Cancer Detection and Diagnosis Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Aug 16, 2022 |
| Last Updated Date: | Aug 16, 2022 |
| Original Closing Date for Applications: | Nov 07, 2022 |
| Current Closing Date for Applications: | Nov 07, 2022 |
| Archive Date: | Dec 13, 2022 |
| Estimated Total Program Funding: | $600,000 |
| Award Ceiling: | $400,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education For profit organizations other than small businesses State governments City or township governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Small businesses Independent school districts Public housing authorities/Indian housing authorities Public and State controlled institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) is a part of an initiative designed to establish a Liver Cancer Consortium to advance translational research focused on early detection of liver cancer. The Consortium will consist of a Data Management and Coordinating Center (DMCC, to be supported by this U24 FOA) and several Translational Research Centers (TRCs, to be supported by the companion U01 FOA, RFA-CA-22-031). The TRCs will conduct studies to improve the surveillance of liver cancer in high-risk populations, increase the fraction of liver cancer detected at an early stage, and better stratify patients at risk of developing liver cancer. The DMCC will support the TRCs and coordinate trans-Consortium activities with the following specific responsibilities: (1) Overall administrative and logistical coordination for the Liver Cancer Consortium; (2) Support for Consortium collaborative research studies and biospecimen collections, including protocol development, data processing, statistical support, and computational analysis; and (3) Consortium data management, including developing and maintaining an integrated database of research data generated by the consortium, as well as management of all data relevant to biospecimens used in TRC studies (including clinical data annotations, and specimen usage tracking). To achieve these goals, the DMCC is expected to provide multi-disciplinary expertise in liver cancer research, biomarkers for cancer detection, biostatistics, bioinformatics, and the information technology infrastructure to support data management for the Consortium. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-CA-22-032.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 343133 Full Announcement-RFA-CA-22-032 -> RFA-CA-22-032-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-G | Use for due dates on or after January 25, 2022 | PKG00276452 | Oct 07, 2022 | Nov 07, 2022 | View | |
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00277615 | Oct 31, 2022 | Nov 07, 2022 | View |
Package 1
Mandatory forms
343133 RR_SF424_5_0-5.0.pdf
343133 PHS398_CoverPageSupplement_5_0-5.0.pdf
343133 RR_OtherProjectInfo_1_4-1.4.pdf
343133 PerformanceSite_4_0-4.0.pdf
343133 RR_KeyPersonExpanded_4_0-4.0.pdf
343133 RR_Budget_3_0-3.0.pdf
343133 PHS398_ResearchPlan_4_0-4.0.pdf
343133 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
343133 RR_SubawardBudget30_3_0-3.0.pdf
343133 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 2
Mandatory forms
343133 RR_SF424_5_0-5.0.pdf
343133 PHS398_CoverPageSupplement_5_0-5.0.pdf
343133 RR_OtherProjectInfo_1_4-1.4.pdf
343133 PerformanceSite_4_0-4.0.pdf
343133 RR_KeyPersonExpanded_4_0-4.0.pdf
343133 RR_Budget_3_0-3.0.pdf
343133 PHS398_ResearchPlan_5_0-5.0.pdf
343133 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
343133 RR_SubawardBudget30_3_0-3.0.pdf
343133 PHS_AssignmentRequestForm_3_0-3.0.pdf
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