The National Cancer Institute (NCI) is offering this grant to support the development and characterization of advanced biomimetic tissue-engineered technologies for cancer research. This grant is for multidisciplinary, collaborative projects that integrate fields such as regenerative medicine, tissue engineering, biomaterials, and bioengineering with cancer biology. The primary purpose is to generate novel experimental models that accurately mimic cancer pathophysiology, providing a robust platform for testable cancer research hypotheses. Supported projects will join the Cancer Tissue Engineering Collaborative (TEC) Research Program. The Cancer TEC Program aims to catalyze the advancement and expansion of innovative in vitro and ex vivo systems across various cancer types, and to promote deeper exploration of cancer phenomena using these biomimetic systems.
Opportunity ID: 357332
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-25-171 |
| Funding Opportunity Title: | Cancer Tissue Engineering Collaborative: Enabling Biomimetic Tissue-Engineered Technologies for Cancer Research (R01 Clinical Trial Optional) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.393 — Cancer Cause and Prevention Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Nov 22, 2024 |
| Last Updated Date: | Nov 22, 2024 |
| Original Closing Date for Applications: | May 07, 2025 |
| Current Closing Date for Applications: | May 07, 2025 |
| Archive Date: | Jun 12, 2025 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $400,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Public and State controlled institutions of higher education State governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Native American tribal governments (Federally recognized) County governments For profit organizations other than small businesses Others (see text field entitled “Additional Information on Eligibility” for clarification) Independent school districts Native American tribal organizations (other than Federally recognized tribal governments) Special district governments Public housing authorities/Indian housing authorities |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | Through this Notice of Funding Opportunity (NOFO), the National cancer Institute (NCI) will support the development and characterization of state-of-the-art biomimetic tissue-engineered technologies for cancer research. Collaborative, multidisciplinary projects that engage the fields of regenerative medicine, tissue engineering, biomaterials, and bioengineering with cancer biology will be essential for generating novel experimental models that mimic cancer pathophysiology in the context of a testable cancer research hypothesis. The projects supported by this NOFO will collectively participate in the Cancer Tissue Engineering Collaborative (TEC) Research Program. The Cancer TEC Program will (1) catalyze the advancement of innovative, well characterized in vitro and ex vivo systems available for cancer research, (2) expand the breadth of these systems to several cancer types, and (3) promote the exploration of cancer phenomena with biomimetic tissue-engineered systems. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/pa-files/PAR-25-171.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 357332 Full Announcement-PAR-25-171 -> PAR-25-171-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00288947 | Jan 05, 2025 | May 07, 2025 | View |
Package 1
Mandatory forms
357332 RR_SF424_5_0-5.0.pdf
357332 PHS398_CoverPageSupplement_5_0-5.0.pdf
357332 RR_OtherProjectInfo_1_4-1.4.pdf
357332 PerformanceSite_4_0-4.0.pdf
357332 RR_KeyPersonExpanded_4_0-4.0.pdf
357332 PHS398_ResearchPlan_5_0-5.0.pdf
357332 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
357332 RR_Budget_3_0-3.0.pdf
357332 RR_SubawardBudget30_3_0-3.0.pdf
357332 PHS398_ModularBudget_1_2-1.2.pdf
357332 PHS_AssignmentRequestForm_4_0-4.0.pdf
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