This grant from the National Cancer Institute (NCI) is for promoting transformative discoveries in cancer biology and oncology through nanotechnology. It encourages applications that address major barriers in these fields using nanotechnology, with a strong emphasis on mechanistic studies. The grant aims to foster a fundamental understanding of how nanomaterials and nanodevices interact with biological systems. Projects should focus on research concerning the delivery of nanoparticles and nanodevices to specific cancer targets in vivo, or the characterization of detection and diagnostic devices in vitro. The ultimate purpose of this funding is to produce foundational knowledge that will support the future and more informed development of nanotechnology-based cancer interventions, excluding clinical translation.
Opportunity ID: 357274
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-25-106 |
| Funding Opportunity Title: | Innovative Research in Cancer Nanotechnology (IRCN; R01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.394 — Cancer Detection and Diagnosis Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Nov 21, 2024 |
| Last Updated Date: | Nov 21, 2024 |
| Original Closing Date for Applications: | May 04, 2026 |
| Current Closing Date for Applications: | May 04, 2026 |
| Archive Date: | Jun 09, 2026 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $475,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Others (see text field entitled “Additional Information on Eligibility” for clarification) Independent school districts City or township governments State governments Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses County governments Special district governments Public housing authorities/Indian housing authorities Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) encourages applications promoting transformative discoveries in cancer biology and/or oncology through the use of nanotechnology. Proposed projects should address major barriers in cancer biology and/or oncology using nanotechnology and should emphasize mechanistic studies toward fundamental understanding of nanomaterial and/or nanodevice interactions with biological systems. These studies should be performed in context of research concerning the delivery of nanoparticles and/or nano-devices to desired and intended cancer targets in vivo and/or characterization of detection and diagnostic devices in vitro. IRCN awards are expected to produce fundamental knowledge to aid future and more informed development of nanotechnology-based cancer interventions. The clinical translation of these interventions is outside of the scope of this NOFO. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/pa-files/PAR-25-106.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 357274 Full Announcement-PAR-25-106 -> PAR-25-106-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00288856 | Apr 05, 2025 | May 04, 2026 | View |
Package 1
Mandatory forms
357274 RR_SF424_5_0-5.0.pdf
357274 PHS398_CoverPageSupplement_5_0-5.0.pdf
357274 RR_OtherProjectInfo_1_4-1.4.pdf
357274 PerformanceSite_4_0-4.0.pdf
357274 RR_KeyPersonExpanded_4_0-4.0.pdf
357274 PHS398_ResearchPlan_5_0-5.0.pdf
357274 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
357274 RR_Budget_3_0-3.0.pdf
357274 RR_SubawardBudget30_3_0-3.0.pdf
357274 PHS398_ModularBudget_1_2-1.2.pdf
357274 PHS_AssignmentRequestForm_4_0-4.0.pdf
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