This National Cancer Institute (NCI) grant is for the purpose of funding transdisciplinary studies that enhance our understanding of the dynamics and underlying mechanisms linking obesity, metabolic dysregulation, and increased cancer risk. Specifically, it focuses on metabolic dysregulation, defined as alterations in glucose utilization, insulin sensitivity, or lipid metabolism, as the key process. Proposals should advance knowledge of how metabolic dysregulation affects cancer risk and identify mechanisms to improve cancer risk prediction, screening for high-risk individuals, and identify targets for preventive and therapeutic interventions. This grant contributes to the broader Metabolic Dysregulation and Cancer Risk Program.
Opportunity ID: 334577
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-CA-21-021 |
| Funding Opportunity Title: | Metabolic Dysregulation and Cancer Risk Program, Research Grants: a Transdisciplinary Approach to Obesity-Associated Research (U01 Clinical Trial Optional) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.393 — Cancer Cause and Prevention Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jul 06, 2021 |
| Last Updated Date: | Jul 06, 2021 |
| Original Closing Date for Applications: | Oct 06, 2021 |
| Current Closing Date for Applications: | Oct 06, 2021 |
| Archive Date: | Nov 11, 2021 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $850,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Special district governments For profit organizations other than small businesses Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) State governments Independent school districts City or township governments Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) Private institutions of higher education County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Public housing authorities/Indian housing authorities |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The National Cancer Institute (NCI) invites research grant proposals for transdisciplinary studies that will enhance our knowledge of the dynamics and underlying mechanisms that link obesity, metabolic dysregulation and increased cancer risk. Through this Funding Opportunity Announcement (FOA), the Metabolic Dysregulation and Cancer Risk Program will focus on metabolic dysregulation as the key process linking obesity with cancer risk. For the purpose of this FOA, metabolic dysregulation is defined as alterations in glucose utilization and storage, insulin sensitivity, and/or lipid metabolism. Proposals should specifically seek to advance our understanding of how metabolic dysregulation in individuals affects cancer risk and identify mechanisms that will enhance (i) cancer risk prediction, (ii) screening for high-risk individuals in clinical settings, and (iii) identification of potential targets for preventive and therapeutic interventions. This FOA is published in parallel with RFA-CA-21-022 Coordinating Center for the Metabolic Dysregulation and Cancer Risk Program: a Transdisciplinary Approach to Obesity-associated Research (U24 Clinical Trial Not Allowed). The individual research grants and the Coordinating Center funded under these FOAs together will constitute the Metabolic Dysregulation and Cancer Risk Program. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-CA-21-021.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-F | Use for due dates on or before January 24, 2022 | PKG00268078 | Sep 06, 2021 | Jan 24, 2022 | View |
Package 1
Mandatory forms
334577 RR_SF424_2_0-2.0.pdf
334577 PHS398_CoverPageSupplement_5_0-5.0.pdf
334577 RR_OtherProjectInfo_1_4-1.4.pdf
334577 PerformanceSite_2_0-2.0.pdf
334577 RR_KeyPersonExpanded_2_0-2.0.pdf
334577 PHS398_ResearchPlan_4_0-4.0.pdf
334577 PHSHumanSubjectsAndClinicalTrialsInfo_2_0-2.0.pdf
Optional forms
334577 RR_Budget_1_4-1.4.pdf
334577 RR_SubawardBudget30_1_4-1.4.pdf
334577 PHS398_ModularBudget_1_2-1.2.pdf
334577 PHS_AssignmentRequestForm_3_0-3.0.pdf
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