This grant is for the critical purpose of renewing the MACS/WIHS Combined Cohort Study (MWCCS) for a six-year period (2026-2032). It aims to continue the comprehensive follow-up of approximately 5,600 middle-aged and older participants, encompassing individuals living with HIV and comparable uninfected counterparts across the United States. The initiative will employ a populomics approach, investigating diverse health determinants—from molecular to sociopolitical levels—using multidisciplinary methods. The ultimate goal is to understand the complex web of influences impacting the health, quality of life, and survival of adults living with HIV. This specific funding opportunity seeks a single Leadership and Coordination Center (LACC) to manage and oversee the entire MWCCS.
Opportunity ID: 358280
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-HL-26-011 |
| Funding Opportunity Title: | Leadership and Coordination Center (LACC) for the MACS/WIHS Combined Cohort Study (MWCCS) (U01 Clinical Trials Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Education Health Income Security and Social Services |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.121 — Oral Diseases and Disorders Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jan 16, 2025 |
| Last Updated Date: | Jan 16, 2025 |
| Original Closing Date for Applications: | May 02, 2025 |
| Current Closing Date for Applications: | May 02, 2025 |
| Archive Date: | Jun 07, 2025 |
| Estimated Total Program Funding: | $2,000,000 |
| Award Ceiling: | $2,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) For profit organizations other than small businesses Private institutions of higher education Special district governments Independent school districts Native American tribal governments (Federally recognized) City or township governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Small businesses Public housing authorities/Indian housing authorities State governments Native American tribal organizations (other than Federally recognized tribal governments) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this Notice of Funding Opportunity (NOFO) is to renew the MACS/WIHS Combined Cohort Study of HIV in United States Adults (MWCCS) for a 6-year project period (2026-2032). Continuation of this epidemiological cohort study of middle-aged and older people living with HIV (PLWH), along with comparable individuals living without HIV (PLWOH) will enable the continued follow-up of a deeply phenotyped cohort of approximately 5,600 participants from across the United States. This initiative will utilize a populomics approach, i.e., examination of health determinants across multiple scales of influence (e.g. molecular, cellular, physiological, lifestyle/behavioral, household, neighborhood, environmental, cultural, and sociopolitical) using multi-disciplinary methods to investigate the web of influences impacting the health, quality of life, and survival of adults living with HIV. This NOFO seeks applications to fund a single Leadership and Coordination Center (LACC) for the MWCCS. This NOFO runs in parallel with two companion U01 NOFOs: RFA-HL-26-009 (Limited Competition: Clinical Research Sites (CRS) for the MACS/WIHS Combined Cohort Study (MWCCS) (U01 Clinical Trials Not Allowed)) and RFA-HL-26-010 (Limited Competition: Data Analysis and Sharing Center (DASC) for the MACS/WIHS Combined Cohort Study (MWCCS) (U01 Clinical Trials Not Allowed)) |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-HL-26-011.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 358280 Full Announcement-RFA-HL-26-011 -> RFA-HL-26-011-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00290177 | Apr 02, 2025 | May 02, 2025 | View |
Package 1
Mandatory forms
358280 RR_SF424_5_0-5.0.pdf
358280 PHS398_CoverPageSupplement_5_0-5.0.pdf
358280 RR_OtherProjectInfo_1_4-1.4.pdf
358280 PerformanceSite_4_0-4.0.pdf
358280 RR_KeyPersonExpanded_4_0-4.0.pdf
358280 RR_Budget10_3_0-3.0.pdf
358280 PHS398_ResearchPlan_5_0-5.0.pdf
358280 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
358280 RR_SubawardBudget10_30_3_0-3.0.pdf
358280 PHS_AssignmentRequestForm_4_0-4.0.pdf
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