This National Human Genome Research Institute (NHGRI) grant aims to establish a Data Analysis and Coordination Center (DACC) as part of a collaborative initiative. The DACC will advance multi-omic technologies for studying health and disease across diverse populations, working alongside Disease Study Sites and Omics Production Centers. Its primary goals include exploring multi-omics integrated with phenotypic, environmental, and social determinants of health data to identify molecular profiles. The DACC will also develop generalizable data harmonization, integration, and analysis methods, establishing best practices and standards. Furthermore, it is responsible for creating a comprehensive multi-dimensional dataset accessible to the research community. Key responsibilities encompass consortium coordination, data management, and contributing to shared protocol and methods development. This initiative focuses on validating and enhancing broad multi-omic approaches.
Opportunity ID: 343376
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-HG-22-010 |
| Funding Opportunity Title: | Multi-Omics for Health and Disease – Data Analysis and Coordination Center (U01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Education Environment Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.113 — Environmental Health |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Sep 07, 2022 |
| Last Updated Date: | Sep 07, 2022 |
| Original Closing Date for Applications: | Nov 18, 2022 |
| Current Closing Date for Applications: | Nov 18, 2022 |
| Archive Date: | Dec 24, 2022 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $950,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | For profit organizations other than small businesses Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities Special district governments State governments City or township governments Native American tribal governments (Federally recognized) Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education County governments Native American tribal organizations (other than Federally recognized tribal governments) Small businesses Others (see text field entitled “Additional Information on Eligibility” for clarification) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The goal of this Funding Opportunity Announcement (FOA) is to establish a Data Analysis and Coordination Center (DACC) that will be part of a collaborative initiative to advance the application of multi-omic technologies to study health and disease in diverse populations. Together with the Disease Study Sites (RFA-HG-22-008) and the Omics Production Center(s) (RFA-HG-22-009), the DACC will leverage clinical conditions where multi-omic approaches are expected to be most informative to: 1) explore the use of multi-omics, integrated with phenotypic and environmental exposure data, including social determinants of health (SDOH), to detect and assess molecular profiles associated with healthy and disease states; 2) develop generalizable data harmonization, integration, and analysis methods, as well as best practices and standards for the optimal application of multi-omics; and 3) create a multi-dimensional dataset that is available to the research community. The DACC will be primarily responsible for coordinating Consortium logistics, outreach, and dissemination of findings; for managing and securing Consortium data; for creating the multi-dimensional dataset; and for coordinating and contributing to consortium-wide protocol development, data analysis, and methods development efforts. While this program may provide some insights into disease etiology, its primary goal is to validate and enhance generalizable multi-omic approaches to identify meaningful biological changes related to health and disease. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-HG-22-010.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 343376 Full Announcement-RFA-HG-22-010 -> RFA-HG-22-010-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-G | Use for due dates on or after January 25, 2022 | PKG00276677 | Oct 18, 2022 | Nov 18, 2022 | View | |
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00277985 | Nov 04, 2022 | Nov 18, 2022 | View |
Package 1
Mandatory forms
343376 RR_SF424_5_0-5.0.pdf
343376 PHS398_CoverPageSupplement_5_0-5.0.pdf
343376 RR_OtherProjectInfo_1_4-1.4.pdf
343376 PerformanceSite_4_0-4.0.pdf
343376 RR_KeyPersonExpanded_4_0-4.0.pdf
343376 PHS398_ResearchPlan_4_0-4.0.pdf
343376 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
343376 RR_Budget_3_0-3.0.pdf
343376 RR_SubawardBudget30_3_0-3.0.pdf
343376 PHS398_ModularBudget_1_2-1.2.pdf
343376 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 2
Mandatory forms
343376 RR_SF424_5_0-5.0.pdf
343376 PHS398_CoverPageSupplement_5_0-5.0.pdf
343376 RR_OtherProjectInfo_1_4-1.4.pdf
343376 PerformanceSite_4_0-4.0.pdf
343376 RR_KeyPersonExpanded_4_0-4.0.pdf
343376 PHS398_ResearchPlan_5_0-5.0.pdf
343376 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
343376 RR_Budget_3_0-3.0.pdf
343376 RR_SubawardBudget30_3_0-3.0.pdf
343376 PHS398_ModularBudget_1_2-1.2.pdf
343376 PHS_AssignmentRequestForm_3_0-3.0.pdf
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