This grant is for advancing innovative non-vaccine biomedical prevention (nBP) strategies, including microbicides, PrEP, and Multipurpose Prevention Technologies (MPT), to combat HIV acquisition and transmission. The National Institute of Allergy and Infectious Diseases (NIAID) aims to support integrated and iterative multi-project preclinical development alongside exploratory clinical studies. The focus is to strengthen the pipeline of nBP candidates by stimulating robust discovery and development. This includes the translation of promising candidates from preclinical stages to pre-Phase I clinical studies, exploring diverse delivery systems for male and female genital and gastrointestinal tracts. Accepted delivery methods encompass gels, films, quick dissolving tablets, intravaginal rings, implants, oral forms, injections, and MPT-based systems. The program seeks to ensure a strong, diverse base in preventing HIV through advanced biomedical solutions.
Opportunity ID: 236732
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AI-13-023 |
| Funding Opportunity Title: | Integrated Preclinical/Clinical Program for HIV Microbicides and Biomedical Prevention (IPCP-MBP) (U19) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.855 — Allergy, Immunology and Transplantation Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jun 24, 2013 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Nov 13, 2013 |
| Current Closing Date for Applications: | Nov 13, 2013 |
| Archive Date: | Dec 14, 2013 |
| Estimated Total Program Funding: | $9,100,000 |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | County governments State governments Small businesses Private institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments City or township governments Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts For profit organizations other than small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this Funding Opportunity Announcement (FOA) is to support integrated and iterative multi-project, multi-disciplinary preclinical development and exploratory clinical studies with the goal of advancing, strengthening and maintaining an innovative pipeline of non-vaccine biomedical prevention (nBP) strategies, including microbicides, PrEP, and Multipurpose Prevention Technologies (MPT). The focus of the IPCP-MBP is to stimulate and support a strong, diverse base in preclinical discovery and development of nBP candidates that includes development of single and combination nBP delivered pericoitally and by sustained delivery systems to the male and female genital and gastrointestinal (GI) tracts to prevent HIV acquisition/transmission. This objective will be accomplished by supporting the translation of candidates and strategies from preclinical to pre-Phase I clinical studies delivered by a variety of drug delivery systems (DDS), including gels, films, quick dissolving tablets, intravaginal rings (IVR), implants, oral, injection and MPT-based DDS strategies. This FOA has significant modifications to previous offerings of the Integrated Preclinical Clinical Program. Applicants are urged to read the FOA carefully. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-AI-13-023.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| MULTI-PROJECT | FORMS-C | PKG00181329 | Oct 13, 2013 | Nov 13, 2013 | View |
Package 1
Mandatory forms
236732 PHS398_ResearchPlan_2_0-2.0.pdf
236732 PHS398_CoverPageSupplement_2_0-2.0.pdf
236732 RR_KeyPersonExpanded_2_0-2.0.pdf
236732 RR_OtherProjectInfo_1_3-1.3.pdf
236732 PerformanceSite_2_0-2.0.pdf
236732 RR_SF424_2_0-2.0.pdf
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