This grant, offered by the National Institute of Environmental Health Sciences (NIEHS), is for understanding how environmental chemical exposures contribute to the development of obesity, type 2 diabetes, and metabolic syndrome. Applications must demonstrate a clear link between specific environmental exposures and increased incidence of weight gain, altered glucose tolerance, or aspects of metabolic syndrome. Research can involve animal models or human studies. While any exposure window is acceptable, emphasis is placed on developmental exposures, such as in utero, neonatal, or early childhood. Human studies should connect these early exposures to biomarkers of disease onset, while animal studies should identify chemicals, affected endpoints, and underlying mechanisms leading to increased disease.
Opportunity ID: 170173
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PA-12-185 |
| Funding Opportunity Title: | Role of Environmental Chemical Exposures in the Development of Obesity, Type 2 Diabetes and Metabolic Syndrome (R01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Environment Food and Nutrition Health Income Security and Social Services |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.113 — Environmental Health |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | May 11, 2012 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Sep 07, 2015 |
| Current Closing Date for Applications: | Sep 07, 2015 |
| Archive Date: | Oct 08, 2015 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Native American tribal organizations (other than Federally recognized tribal governments) State governments Private institutions of higher education Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities Special district governments Independent school districts Others (see text field entitled “Additional Information on Eligibility” for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Public and State controlled institutions of higher education County governments Small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The Funding Opportunity Announcement, issued by the National Institute of Environmental Health Sciences (NIEHS), encourages grant applications to understand the role of environmental chemical exposures in the development of obesity, type 2 diabetes and/or metabolic syndrome. Applications must link an environmental exposure to the increased incidence of weight gain, glucose tolerance/insulin sensitivity and aspects of metabolic syndrome in animal models or human studies. While any exposure window is acceptable it is anticipated that the most sensitive time for exposures to affect the disease outcomes will be during development e.g. in utero and/or neonatal or early childhood. For human studies developmental exposures (in utero and early childhood) should be linked to early biomarkers of disease onset. Animal studies should focus on identifying environmental chemicals that alter endpoints indicative of affecting disease development and the site and mechanism(s) of the effects that lead to the increased disease incidence. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PA-12-185.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| ADOBE-FORMS-B2 | ADOBE-FORMS-B2 | PKG00121311 | Sep 05, 2012 | Sep 24, 2013 | View | |
| FORMS-C | Use for due dates after 9/24/2013. | PKG00180437 | Sep 08, 2013 | Sep 07, 2015 | View |
Package 1
Mandatory forms
170173 RR_SF424_1_2-1.2.pdf
170173 PerformanceSite_1_4-1.4.pdf
170173 RR_OtherProjectInfo_1_3-1.3.pdf
170173 RR_KeyPersonExpanded_1_2-1.2.pdf
170173 PHS398_CoverPageSupplement_1_4-1.4.pdf
170173 PHS398_ResearchPlan_1_3-1.3.pdf
170173 PHS398_Checklist_1_3-1.3.pdf
Optional forms
170173 RR_SubawardBudget30-1.2.pdf
170173 PHS398_ModularBudget_1_2-1.2.pdf
170173 RR_Budget-1.1.pdf
170173 PHS_CoverLetter_1_2-1.2.pdf
Package 2
Mandatory forms
170173 RR_SF424_2_0-2.0.pdf
170173 PHS398_ResearchPlan_2_0-2.0.pdf
170173 PHS398_CoverPageSupplement_2_0-2.0.pdf
170173 RR_KeyPersonExpanded_2_0-2.0.pdf
170173 RR_OtherProjectInfo_1_3-1.3.pdf
170173 PerformanceSite_2_0-2.0.pdf
Optional forms
170173 RR_SubawardBudget30_1_3-1.3.pdf
170173 PlannedReport-1.0.pdf
170173 PHS398_CumulativeInclusionReport-1.0.pdf
170173 PHS398_ModularBudget_1_2-1.2.pdf
170173 RR_Budget_1_3-1.3.pdf
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