This grant, offered by the National Institute on Aging (NIA), is specifically designed to encourage innovative research applications that will significantly enhance the current understanding of underlying mechanisms associated with neuropsychiatric symptoms (NPS) in persons afflicted with Alzheimer’s disease (AD) or Alzheimer’s disease-related dementias (ADRD). This grant is for the purpose of advancing a detailed mechanistic understanding of both biobehavioral and neurobiological pathways that lead to the manifestation of NPS. The expected findings are crucial, as they aim to provide vital insight into novel therapeutic targets. Such discoveries can then be leveraged to develop effective interventions for treating and potentially preventing the development of these challenging symptoms in AD and/or ADRD, ultimately improving patient outcomes.
Opportunity ID: 357200
General Information
Document Type: | Grants Notice |
Funding Opportunity Number: | PAR-25-064 |
Funding Opportunity Title: | Novel Mechanism Research on Neuropsychiatric Symptoms (NPS) in Alzheimer’s Dementia (R21 Clinical Trial Optional) |
Opportunity Category: | Discretionary |
Opportunity Category Explanation: | – |
Funding Instrument Type: | Grant |
Category of Funding Activity: | Health |
Category Explanation: | – |
Expected Number of Awards: | – |
Assistance Listings: | 93.242 — Mental Health Research Grants |
Cost Sharing or Matching Requirement: | No |
Version: | Synopsis 1 |
Posted Date: | Nov 18, 2024 |
Last Updated Date: | Nov 18, 2024 |
Original Closing Date for Applications: | Sep 07, 2026 |
Current Closing Date for Applications: | Sep 07, 2026 |
Archive Date: | Oct 13, 2026 |
Estimated Total Program Funding: | – |
Award Ceiling: | – |
Award Floor: | – |
Eligibility
Eligible Applicants: | Special district governments Public and State controlled institutions of higher education City or township governments Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Public housing authorities/Indian housing authorities Small businesses Independent school districts State governments County governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Others (see text field entitled “Additional Information on Eligibility” for clarification) Native American tribal organizations (other than Federally recognized tribal governments) |
Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
Agency Name: | National Institutes of Health |
Description: | The goal of this Funding Opportunity Announcement (FOA) is to encourage applications for studies that will enhance knowledge of mechanisms associated with neuropsychiatric symptoms (NPS) in persons with Alzheimer’s disease (AD) or Alzheimer’s disease-related dementias (ADRD). The findings are expected to advanceadavnce mechanistic understanding of both biobehavioral and neurobiologfical pathways leading to NPS. Findings may also provide insight into novel therapeutic targets that can be advanced into interventions to treat and prevent the development of NPS in AD and/or ADRD. |
Link to Additional Information: | https://grants.nih.gov/grants/guide/pa-files/PAR-25-064.html |
Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
Version | Modification Description | Updated Date |
---|---|---|
Related Documents
Folder 357200 Full Announcement-PAR-25-064 -> PAR-25-064-Full-Announcement.pdf
Packages
Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
Who Can Apply: | Organization Applicants |
Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
---|---|---|---|---|---|---|
FORMS-I | Use for due dates on or after January 25, 2025 | PKG00288789 | Jan 16, 2025 | Sep 07, 2026 | View |
Package 1
Mandatory forms
357200 RR_SF424_5_0-5.0.pdf
357200 PHS398_CoverPageSupplement_5_0-5.0.pdf
357200 RR_OtherProjectInfo_1_4-1.4.pdf
357200 PerformanceSite_4_0-4.0.pdf
357200 RR_KeyPersonExpanded_4_0-4.0.pdf
357200 PHS398_ResearchPlan_5_0-5.0.pdf
357200 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
357200 RR_Budget_3_0-3.0.pdf
357200 RR_SubawardBudget30_3_0-3.0.pdf
357200 PHS398_ModularBudget_1_2-1.2.pdf
357200 PHS_AssignmentRequestForm_4_0-4.0.pdf