This grant is for the purpose of advancing influenza immunity through the Computational Models of Influenza Immunity Cooperative Agreement Program. It utilizes computational modeling and immunologic studies to identify requirements for improving anti-influenza immunity, focusing on broad protection and immune durability. The program aims to inform the design of universal or improved seasonal flu vaccines by understanding how pre-existing immunity and repeat exposures influence the immune landscape. Through predictive modeling of adjuvants/vaccine formulations and experimental validation, this initiative seeks to enhance host immune responses and improve the efficacy of universal or seasonal influenza vaccines.
Opportunity ID: 350198
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AI-23-056 |
| Funding Opportunity Title: | Computational Models of Influenza Immunity (U01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.855 — Allergy and Infectious Diseases Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Sep 13, 2023 |
| Last Updated Date: | Sep 13, 2023 |
| Original Closing Date for Applications: | Jan 26, 2024 |
| Current Closing Date for Applications: | Jan 26, 2024 |
| Archive Date: | Mar 02, 2024 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $750,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | County governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Public housing authorities/Indian housing authorities For profit organizations other than small businesses Others (see text field entitled “Additional Information on Eligibility” for clarification) State governments Special district governments Private institutions of higher education Small businesses Independent school districts Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Notice of Funding Opportunity (NOFO) invites applications for the Computational Models of Influenza Immunity Cooperative Agreement Program. The program will employ computational modeling and immunologic studies to advance our understanding of the requirements for improving anti-influenza immunity, including inducing broad immune protection and enhancing immune durability. This program will help inform design of universal or improved seasonal flu vaccines. Projects may lead to a better understanding of how pre-existing immunity and repeat exposures (natural infection and/or vaccines) shape an individuals immune landscape. Predictive modeling of adjuvants/vaccine formulations and experimental validation supported by this program should lead to enhanced host immune responses and universal or improved seasonal influenza vaccine efficacy. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-AI-23-056.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 350198 Full Announcement-RFA-AI-23-056 -> RFA-AI-23-056-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00283149 | Dec 26, 2023 | Jan 26, 2024 | View |
Package 1
Mandatory forms
350198 RR_SF424_5_0-5.0.pdf
350198 PHS398_CoverPageSupplement_5_0-5.0.pdf
350198 RR_OtherProjectInfo_1_4-1.4.pdf
350198 PerformanceSite_4_0-4.0.pdf
350198 RR_KeyPersonExpanded_4_0-4.0.pdf
350198 PHS398_ResearchPlan_5_0-5.0.pdf
350198 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
350198 RR_Budget_3_0-3.0.pdf
350198 RR_SubawardBudget30_3_0-3.0.pdf
350198 PHS398_ModularBudget_1_2-1.2.pdf
350198 PHS_AssignmentRequestForm_3_0-3.0.pdf