This grant is for the purpose of supporting innovative research on developing biomarkers for complications of type 1 diabetes. It specifically focuses on projects utilizing minimally or non-invasive methods to assess blood vessels and nerves in the eye. A significant obstacle in preventing and treating diabetes complications is the current lack of biomarkers that can detect subtle changes before clinical signs emerge, as well as surrogate endpoints to gauge early intervention responses. Given the eye’s unique accessibility for visualization, this funding opportunity encourages applications leveraging ocular measures to identify the development of diabetes complications. The research should aim to visualize these complications not only within the eye but also to infer changes in other critical tissues, including the kidney, brain, heart, and peripheral nerves.
Opportunity ID: 246896
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DK-13-027 |
| Funding Opportunity Title: | Biomarkers for Diabetes Complications – Non-Invasive Measures in the Eye (DP3) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Food and Nutrition Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.847 — Diabetes, Digestive, and Kidney Diseases Extramural Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Nov 06, 2013 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Apr 07, 2014 |
| Current Closing Date for Applications: | Apr 07, 2014 |
| Archive Date: | May 08, 2014 |
| Estimated Total Program Funding: | $7,500,000 |
| Award Ceiling: | $1,000,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | State governments City or township governments For profit organizations other than small businesses County governments Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Private institutions of higher education Small businesses Special district governments Public housing authorities/Indian housing authorities Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This FOA will support research on the development of biomarkers for the complications of type 1 diabetes that will use minimally or non-invasive measures of blood vessels and nerves in the eye. A critical obstacle for preventing and treating diabetes complications is the paucity of both biomarkers that can detect changes in blood vessels and nerves before clinical signs develop and surrogate end-points that can measure early responses to an intervention. Given the accessibility of the blood vessels and nerves in the eye for visualization, this FOA invites applications for research using the eye to visualize the development of diabetes complications in the eye and other tissues, such as the kidney, brain, heart and peripheral nerves. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-13-027.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| 93.847 | FORMS-C | Forms-C | PKG00188870 | Mar 07, 2014 | Apr 07, 2014 | View |
Package 1
Mandatory forms
246896 RR_SF424_2_0-2.0.pdf
246896 PHS398_ResearchPlan_2_0-2.0.pdf
246896 RR_KeyPersonExpanded_2_0-2.0.pdf
246896 RR_OtherProjectInfo_1_3-1.3.pdf
246896 PerformanceSite_2_0-2.0.pdf
Optional forms
246896 PHS398_CumulativeInclusionReport-1.0.pdf
246896 PlannedReport-1.0.pdf
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