This grant from the National Institutes of Health (NIH) is for promoting foundational research into the complex interplay of mitochondrial function and aging. Specifically, it targets investigations into both protective and pathogenic mechanisms at the nexus of mitochondria, aging, HIV infection, and substance use disorders (SUD). The core purpose is to generate critical knowledge that can be leveraged to develop new, targeted therapies. This initiative aims to improve health outcomes and enhance the quality of life for people navigating the challenges of aging with HIV, substance use, and addiction. Understanding these mitochondrial-associated mechanisms is crucial for advancing precision medicine in these vulnerable populations.
Opportunity ID: 356597
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DA-26-010 |
| Funding Opportunity Title: | Mitochondrial-associated Mechanisms of Neuropathological and Immunodeficient Aging in the Context of HIV and SUD (R21 Clinical Trials Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.279 — Drug Abuse and Addiction Research Programs |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Sep 30, 2024 |
| Last Updated Date: | Sep 30, 2024 |
| Original Closing Date for Applications: | Mar 10, 2026 |
| Current Closing Date for Applications: | Mar 10, 2026 |
| Archive Date: | Apr 15, 2026 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Private institutions of higher education Independent school districts County governments Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities City or township governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Special district governments Others (see text field entitled “Additional Information on Eligibility” for clarification) State governments Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | To promote research investigating protective and pathogenic mechanisms at the nexus of mitochondria function and aging in the context of HIV infection and exposure to addictive substances. We anticipate this foundational knowledge could be leveraged to develop targeted therapies and improve outcomes in people aging with HIV, substance use and addiction. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-26-010.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 356597 Full Announcement-RFA-DA-26-010 -> RFA-DA-26-010-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00288385 | Feb 10, 2025 | Mar 10, 2026 | View |
Package 1
Mandatory forms
356597 RR_SF424_5_0-5.0.pdf
356597 PHS398_CoverPageSupplement_5_0-5.0.pdf
356597 RR_OtherProjectInfo_1_4-1.4.pdf
356597 PerformanceSite_4_0-4.0.pdf
356597 RR_KeyPersonExpanded_4_0-4.0.pdf
356597 PHS398_ResearchPlan_5_0-5.0.pdf
356597 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
356597 RR_Budget_3_0-3.0.pdf
356597 RR_SubawardBudget30_3_0-3.0.pdf
356597 PHS398_ModularBudget_1_2-1.2.pdf
356597 PHS_AssignmentRequestForm_4_0-4.0.pdf
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