This NCI grant, the Early Detection Research Network (EDRN) Biomarker Developmental Laboratories (U01), is for laboratories focused on the development and characterization of new, or the refinement of existing, biomarkers and biomarker assays. This grant is for the purpose of advancing early cancer detection, risk assessment, and molecular diagnosis/prognosis of early cancer by contributing to the EDRN’s overall mission. As a critical component of the national EDRN consortium, successful applicants will collaborate with other network elements like Biomarker Reference Laboratories and Clinical Validation Centers. The National Cancer Institute anticipates funding 20-25 BDLs, committing $10-11 million annually to support these crucial efforts in biomarker discovery and validation for early cancer diagnosis.
Opportunity ID: 48158
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-CA-09-017 |
| Funding Opportunity Title: | The Early Detection Research Network: Biomarker Developmental Laboratories (U01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.393 — Cancer Cause and Prevention Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jun 26, 2009 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Oct 29, 2009 |
| Current Closing Date for Applications: | Oct 29, 2009 |
| Archive Date: | Nov 29, 2009 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $400,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | For profit organizations other than small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Public and State controlled institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Eligible Agencies of the Federal Government; Non-domestic (non-U.S.) Entities (Foreign Organizations); U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | Purpose. This funding opportunity announcement (FOA) solicits cooperative agreement applications for Biomarker Developmental Laboratories (BDLs), one of the four components of the Early Detection Research Network (EDRN). EDRN is a national consortium funded to discover, develop, and validate biomarkers for early cancer detection, risk assessment, and the molecular diagnosis and prognosis of early cancer.. The BDLs have responsibility for the development and characterization of new, or the refinement of existing, biomarkers and biomarker assays. The other three main components of the EDRN are: the Biomarker Reference Laboratories (BRLs), which serve as Network resources for clinical and laboratory validation of biomarkers; the Clinical Validation Centers (CVCs), which conduct clinical research on the validation of biomarkers in early cancer detection and risk assessment and serve as resource centers for the EDRN by participating in collaborative biomarker validation studies and collaborating with EDRN BDLs and BRLs; and the Data Management and Coordinating Center (DMCC), which supports statistical and computational analyses, informatics infrastructure, and the coordination of network-wide meetings and conferences. Mechanism of Support. This FOA utilizes the NIH Cooperative Agreement (U01) award mechanism. Parallel FOAs for other EDRN components include RFA-CA-09-018 (U01) for CVCs, RFA-CA-09-019 (U24) for BRLs, and RFA-CA-09-020 (U24) for DMCC. Funds Available and Anticipated Number of Awards. The NCI expects to commit $10-11 million per year to fund 20 – 25 BDLs. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-CA-09-017.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
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