This grant, available as an R21 exploratory and developmental Grant, is specifically designed to stimulate crucial research into noncoding ribonucleic acids (ncRNAs) within the context of Alzheimer’s disease and related dementias (AD/ADRD). Its primary purpose is to support investigations aimed at uncovering the causality, directionality, and underlying mechanisms of ncRNAs implicated in AD/ADRD, while also rigorously assessing their therapeutic potential. Proposed studies must focus on discovering the functional roles of ncRNAs in disease pathogenesis and progression. A key requirement is the detailed functional characterization and mechanistic investigation of ncRNAs that have been previously identified, seeking to advance our understanding of these critical molecular players in neurodegenerative conditions and potentially identify new therapeutic avenues.
Opportunity ID: 338419
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AG-23-011 |
| Funding Opportunity Title: | Noncoding RNAs in Alzheimers Disease and Related Dementias (R21 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.866 — Aging Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Feb 28, 2022 |
| Last Updated Date: | Feb 28, 2022 |
| Original Closing Date for Applications: | Jul 15, 2022 |
| Current Closing Date for Applications: | Jul 15, 2022 |
| Archive Date: | Aug 20, 2022 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Private institutions of higher education For profit organizations other than small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments State governments Small businesses Independent school districts Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled “Additional Information on Eligibility” for clarification) County governments Native American tribal governments (Federally recognized) City or township governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The goal of this Funding Opportunity Announcement (FOA) is to stimulate research in noncoding ribonucleic acids (ncRNAs) to investigate the causality, directionality, mechanisms, and therapeutic potential of ncRNAs implicated in Alzheimer’s disease and Alzheimer’s disease related dementias (AD/ADRD). This FOA will support exploratory and developmental Grant (R21) applications seeking to discover functional roles of ncRNAs and underlying mechanisms involved in the pathogenesis and progression of AD/ADRD. Proposed studies should focus on functional characterization and mechanistic investigation of previously identified ncRNAs. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-23-011.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
OERWebmaster03@od.nih.gov Email:OERWebmaster03@od.nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster OERWebmaster03@od.nih.gov Email: OERWebmaster03@od.nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-G | Use for due dates on or after January 25, 2022 | PKG00272274 | Jun 15, 2022 | Jul 15, 2022 | View |
Package 1
Mandatory forms
338419 RR_SF424_5_0-5.0.pdf
338419 PHS398_CoverPageSupplement_5_0-5.0.pdf
338419 RR_OtherProjectInfo_1_4-1.4.pdf
338419 PerformanceSite_4_0-4.0.pdf
338419 RR_KeyPersonExpanded_4_0-4.0.pdf
338419 PHS398_ResearchPlan_4_0-4.0.pdf
338419 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
338419 RR_Budget_3_0-3.0.pdf
338419 RR_SubawardBudget30_3_0-3.0.pdf
338419 PHS398_ModularBudget_1_2-1.2.pdf
338419 PHS_AssignmentRequestForm_3_0-3.0.pdf
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