This grant is designed to support studies investigating the critical role of epigenetic mechanisms in regulating HIV CNS (central nervous system) latency and neuropathogenesis. It specifically encourages research focused on how these mechanisms operate within brain-derived cells, including macrophages, microglia, and astrocytes. A key aspect of this funding opportunity is the application of novel single cell technologies to unravel the complexities of HIV infection and its impact on the brain. The primary purpose is to enhance understanding of HIV persistence and neurological complications, ultimately contributing to the development of improved therapeutic strategies. This initiative seeks innovative proposals utilizing advanced cellular analysis techniques.
Opportunity ID: 342107
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-MH-22-281 |
| Funding Opportunity Title: | Epigenetic Mechanisms Regulating HIV CNS Latency and Neuropathogenesis Using Novel Single Cell Technologies (R21 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.242 — Mental Health Research Grants |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jul 12, 2022 |
| Last Updated Date: | Jul 12, 2022 |
| Original Closing Date for Applications: | Dec 05, 2022 |
| Current Closing Date for Applications: | Dec 05, 2022 |
| Archive Date: | Jan 10, 2023 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | County governments Special district governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Public and State controlled institutions of higher education State governments City or township governments Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The goal of this initiative is to study the role of epigenetic mechanisms regulating HIV CNS (central nervous system) latency and neuropathogenesis in brain derived cells such as macrophages, microglia and astrocytes using novel single cell technologies. Thus this FOA will encourage studies of the role of epigenetic mechanisms regulating HIV CNS latency and neuropathogenesis in brain derived cells such as macrophages and microglia using novel single cell technologies. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-MH-22-281.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
OERWebmaster03@od.nih.gov Email:OERWebmaster03@od.nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 342107 Full Announcement-RFA-MH-22-281 -> RFA-MH-22-281-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH OER Webmaster OERWebmaster03@od.nih.gov Email: OERWebmaster03@od.nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-G | Use for due dates on or before January 24, 2023 | PKG00275813 | Nov 05, 2022 | Jan 24, 2023 | View | |
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00278182 | Nov 08, 2022 | Dec 05, 2022 | View |
Package 1
Mandatory forms
342107 RR_SF424_5_0-5.0.pdf
342107 PHS398_CoverPageSupplement_5_0-5.0.pdf
342107 RR_OtherProjectInfo_1_4-1.4.pdf
342107 PerformanceSite_4_0-4.0.pdf
342107 RR_KeyPersonExpanded_4_0-4.0.pdf
342107 PHS398_ResearchPlan_4_0-4.0.pdf
342107 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
342107 RR_Budget_3_0-3.0.pdf
342107 RR_SubawardBudget30_3_0-3.0.pdf
342107 PHS398_ModularBudget_1_2-1.2.pdf
342107 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 2
Mandatory forms
342107 RR_SF424_5_0-5.0.pdf
342107 PHS398_CoverPageSupplement_5_0-5.0.pdf
342107 RR_OtherProjectInfo_1_4-1.4.pdf
342107 PerformanceSite_4_0-4.0.pdf
342107 RR_KeyPersonExpanded_4_0-4.0.pdf
342107 PHS398_ResearchPlan_5_0-5.0.pdf
342107 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
342107 RR_Budget_3_0-3.0.pdf
342107 RR_SubawardBudget30_3_0-3.0.pdf
342107 PHS398_ModularBudget_1_2-1.2.pdf
342107 PHS_AssignmentRequestForm_3_0-3.0.pdf
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