This NHLBI Outstanding Investigator Award (OIA) is for experienced Program Directors/Principal Investigators with an exceptional record in heart, lung, blood, and sleep (HLBS) research. Its purpose is to foster scientific productivity and innovation by offering long-term, flexible support for a comprehensive research program, rather than a specific project. This grant enables recipients to pursue high-risk, groundbreaking research that requires extended timelines, free from the constraints of rigid specific aims. It aims to provide a stable funding environment, accelerate scientific discovery, and reduce administrative time spent on multiple grant applications. Ultimately, the OIA empowers leading HLBS investigators to dedicate more effort to research, innovation, and mentoring junior scientists.
Opportunity ID: 353821
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-HL-26-002 |
| Funding Opportunity Title: | NHLBI Outstanding Investigator Award (OIA) (R35 Clinical Trial Optional) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.233 — National Center on Sleep Disorders Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Apr 26, 2024 |
| Last Updated Date: | Apr 26, 2024 |
| Original Closing Date for Applications: | Apr 28, 2027 |
| Current Closing Date for Applications: | Apr 28, 2027 |
| Archive Date: | Jun 03, 2027 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Native American tribal governments (Federally recognized) Others (see text field entitled “Additional Information on Eligibility” for clarification) Native American tribal organizations (other than Federally recognized tribal governments) City or township governments For profit organizations other than small businesses Small businesses Public and State controlled institutions of higher education County governments Special district governments Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of the NHLBI Outstanding Investigator Award (OIA) is to promote scientific productivity and innovation by providing long-term support and increased flexibility to experienced Program Directors/Principal Investigators (PDs/PIs) who are currently PDs/PIs on at least two NHLBI R01-equivalent awards and whose outstanding record of research demonstrates their ability to make major contributions to heart, lung, blood and sleep (HLBS) research. The OIA is intended to support a research program, rather than a research project, by providing the primary and most likely sole source of NHLBI funding on individual grant awards. The OIA will support the research program of NHLBI-funded investigators for up to seven years. The OIA will provide investigators increased freedom to conduct research that breaks new ground or extends previous discoveries in new directions. It will also allow PDs/PIs to take greater risks and to pursue research that requires a longer timeframe. Research supported by the OIA must be within the scope of the NHLBI mission (https://www.nhlbi.nih.gov/about/mission-statement). It is anticipated that the OIA will: Provide a stable funding environment, thereby improving productivity and facilitating nimble, ambitious, creative research; Accelerate scientific innovation by enabling flexibility in pursuing new research directions as they arise, since PDs/PIs will not be bound to specific aims proposed in advance of the studies; Reduce the time researchers spend writing grant applications and managing multiple grant awards, thereby allowing more time to be devoted to conducting research; Facilitate commitment of PDs/PIs to research through increased stability of funding; and Enable PDs/PIs to devote more time and energy to mentoring students and junior scientists and providing scientific service. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-HL-26-002.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00289028 | Jan 19, 2025 | Apr 28, 2027 | View |
Package 1
Mandatory forms
353821 RR_SF424_5_0-5.0.pdf
353821 PHS398_CoverPageSupplement_5_0-5.0.pdf
353821 RR_OtherProjectInfo_1_4-1.4.pdf
353821 PerformanceSite_4_0-4.0.pdf
353821 RR_KeyPersonExpanded_4_0-4.0.pdf
353821 RR_Budget10_3_0-3.0.pdf
353821 PHS398_ResearchPlan_5_0-5.0.pdf
353821 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
353821 RR_SubawardBudget10_30_3_0-3.0.pdf
353821 PHS_AssignmentRequestForm_4_0-4.0.pdf
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