Opportunity ID: 346913

General Information

Document Type: Grants Notice
Funding Opportunity Number: RFA-NS-24-005
Funding Opportunity Title: BRAIN Initiative: Optimization of Instrumentation and Device Technologies for Recording and Modulation in the Nervous System (U01 Clinical Trials Not Allowed)
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Cooperative Agreement
Category of Funding Activity: Education
Health
Income Security and Social Services
Category Explanation:
Expected Number of Awards:
Assistance Listings: 93.173 — Research Related to Deafness and Communication Disorders
Cost Sharing or Matching Requirement: No
Version: Synopsis 2
Posted Date: Mar 16, 2023
Last Updated Date: Sep 24, 2024
Original Closing Date for Applications: Jan 20, 2026
Current Closing Date for Applications: Sep 23, 2024
Archive Date: Oct 23, 2024
Estimated Total Program Funding:
Award Ceiling:
Award Floor:

Eligibility

Eligible Applicants: For profit organizations other than small businesses
Public and State controlled institutions of higher education
City or township governments
County governments
State governments
Others (see text field entitled “Additional Information on Eligibility” for clarification)
Public housing authorities/Indian housing authorities
Native American tribal governments (Federally recognized)
Native American tribal organizations (other than Federally recognized tribal governments)
Small businesses
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Private institutions of higher education
Special district governments
Independent school districts
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Additional Information

Agency Name: National Institutes of Health
Description:

Reissue of RFA-NS-18-019: Understanding the dynamic activity of neural circuits is central to the NIH BRAIN Initiative. The invention, proof-of-concept investigation, and optimization of new technologies through iterative feedback from end users are key components of the BRAIN Initiative. This FOA seeks applications to optimize existing or emerging technologies through iterative testing with end users. The technologies and approaches should have potential to address major challenges associated with recording and modulation (including various modalities for stimulation/activation, inhibition and manipulation) of cells (i.e., neuronal and non-neuronal) and networks to enable transformative understanding of dynamic signaling in the central nervous system (CNS). These technologies and approaches should have previously demonstrated their transformative potential through initial proof-of-concept testing and are now ready for accelerated refinement. In conjunction, the manufacturing techniques should be scalable towards sustainable, broad dissemination and user-friendly incorporation into regular neuroscience research.Proposed technologies should be compatible with experiments in behaving animals, validated under in vivo experimental conditions, and capable of reducing major barriers to conducting neurobiological experiments and making new discoveries about the CNS. Technologies may engage diverse types of signaling beyond neuronal electrical activity such as optical, electrical, magnetic, acoustic or genetic recording/manipulation. Applications that seek to integrate multiple approaches are encouraged. If suitable, applications are expected to integrate appropriate domains of expertise, including biological, chemical and physical sciences, engineering, computational modeling and statistical analysis.

Link to Additional Information: https://grants.nih.gov/grants/guide/rfa-files/RFA-NS-24-005.html
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

NIH Grants Information

grantsinfo@nih.gov
Email:grantsinfo@nih.gov

Version History

Version Modification Description Updated Date
Update close date per issuance of RFA-NS-25-017. Sep 24, 2024
Mar 16, 2023
Mar 23, 2023

DISPLAYING: Synopsis 2

General Information

Document Type: Grants Notice
Funding Opportunity Number: RFA-NS-24-005
Funding Opportunity Title: BRAIN Initiative: Optimization of Instrumentation and Device Technologies for Recording and Modulation in the Nervous System (U01 Clinical Trials Not Allowed)
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Cooperative Agreement
Category of Funding Activity: Education
Health
Income Security and Social Services
Category Explanation:
Expected Number of Awards:
Assistance Listings: 93.173 — Research Related to Deafness and Communication Disorders
Cost Sharing or Matching Requirement: No
Version: Synopsis 2
Posted Date: Mar 16, 2023
Last Updated Date: Sep 24, 2024
Original Closing Date for Applications: Jan 20, 2026
Current Closing Date for Applications: Sep 23, 2024
Archive Date: Oct 23, 2024
Estimated Total Program Funding:
Award Ceiling:
Award Floor:

Eligibility

Eligible Applicants: For profit organizations other than small businesses
Public and State controlled institutions of higher education
City or township governments
County governments
State governments
Others (see text field entitled “Additional Information on Eligibility” for clarification)
Public housing authorities/Indian housing authorities
Native American tribal governments (Federally recognized)
Native American tribal organizations (other than Federally recognized tribal governments)
Small businesses
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Private institutions of higher education
Special district governments
Independent school districts
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Additional Information

Agency Name: National Institutes of Health
Description:

Reissue of RFA-NS-18-019: Understanding the dynamic activity of neural circuits is central to the NIH BRAIN Initiative. The invention, proof-of-concept investigation, and optimization of new technologies through iterative feedback from end users are key components of the BRAIN Initiative. This FOA seeks applications to optimize existing or emerging technologies through iterative testing with end users. The technologies and approaches should have potential to address major challenges associated with recording and modulation (including various modalities for stimulation/activation, inhibition and manipulation) of cells (i.e., neuronal and non-neuronal) and networks to enable transformative understanding of dynamic signaling in the central nervous system (CNS). These technologies and approaches should have previously demonstrated their transformative potential through initial proof-of-concept testing and are now ready for accelerated refinement. In conjunction, the manufacturing techniques should be scalable towards sustainable, broad dissemination and user-friendly incorporation into regular neuroscience research.Proposed technologies should be compatible with experiments in behaving animals, validated under in vivo experimental conditions, and capable of reducing major barriers to conducting neurobiological experiments and making new discoveries about the CNS. Technologies may engage diverse types of signaling beyond neuronal electrical activity such as optical, electrical, magnetic, acoustic or genetic recording/manipulation. Applications that seek to integrate multiple approaches are encouraged. If suitable, applications are expected to integrate appropriate domains of expertise, including biological, chemical and physical sciences, engineering, computational modeling and statistical analysis.

Link to Additional Information: https://grants.nih.gov/grants/guide/rfa-files/RFA-NS-24-005.html
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

NIH Grants Information

grantsinfo@nih.gov
Email:grantsinfo@nih.gov

DISPLAYING: Synopsis 1

General Information

Document Type: Grants Notice
Funding Opportunity Number: RFA-NS-24-005
Funding Opportunity Title: BRAIN Initiative: Optimization of Instrumentation and Device Technologies for Recording and Modulation in the Nervous System (U01 Clinical Trials Not Allowed)
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Cooperative Agreement
Category of Funding Activity: Education
Health
Income Security and Social Services
Category Explanation:
Expected Number of Awards:
Assistance Listings: 93.173 — Research Related to Deafness and Communication Disorders
Cost Sharing or Matching Requirement: No
Version: Synopsis 1
Posted Date: Mar 16, 2023
Last Updated Date: Mar 16, 2023
Original Closing Date for Applications:
Current Closing Date for Applications: Jan 20, 2026
Archive Date: Feb 25, 2026
Estimated Total Program Funding:
Award Ceiling:
Award Floor:

Eligibility

Eligible Applicants: Special district governments
Public and State controlled institutions of higher education
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Small businesses
Native American tribal organizations (other than Federally recognized tribal governments)
Native American tribal governments (Federally recognized)
Private institutions of higher education
City or township governments
Public housing authorities/Indian housing authorities
Others (see text field entitled “Additional Information on Eligibility” for clarification)
State governments
County governments
For profit organizations other than small businesses
Independent school districts
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Additional Information on Eligibility: Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Additional Information

Agency Name: National Institutes of Health
Description: Reissue of RFA-NS-18-019: Understanding the dynamic activity of neural circuits is central to the NIH BRAIN Initiative. The invention, proof-of-concept investigation, and optimization of new technologies through iterative feedback from end users are key components of the BRAIN Initiative. This FOA seeks applications to optimize existing or emerging technologies through iterative testing with end users. The technologies and approaches should have potential to address major challenges associated with recording and modulation (including various modalities for stimulation/activation, inhibition and manipulation) of cells (i.e., neuronal and non-neuronal) and networks to enable transformative understanding of dynamic signaling in the central nervous system (CNS). These technologies and approaches should have previously demonstrated their transformative potential through initial proof-of-concept testing and are now ready for accelerated refinement. In conjunction, the manufacturing techniques should be scalable towards sustainable, broad dissemination and user-friendly incorporation into regular neuroscience research.Proposed technologies should be compatible with experiments in behaving animals, validated under in vivo experimental conditions, and capable of reducing major barriers to conducting neurobiological experiments and making new discoveries about the CNS. Technologies may engage diverse types of signaling beyond neuronal electrical activity such as optical, electrical, magnetic, acoustic or genetic recording/manipulation. Applications that seek to integrate multiple approaches are encouraged. If suitable, applications are expected to integrate appropriate domains of expertise, including biological, chemical and physical sciences, engineering, computational modeling and statistical analysis.
Link to Additional Information: https://grants.nih.gov/grants/guide/rfa-files/RFA-NS-24-005.html
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

NIH Grants Information
grantsinfo@nih.gov
Email:grantsinfo@nih.gov

DISPLAYING: Forecast 1

General Information

Document Type: Grants Notice
Funding Opportunity Number: NOT-NS-23-036
Funding Opportunity Title: Notice of Intent to Publish a Funding Opportunity Announcement for BRAIN Initiative: Optimization of Instrumentation and Device Technologies for Recording and Modulation in the Nervous System (U01 Clinical Trials Not Allowed)
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Cooperative Agreement
Category of Funding Activity: Health
Category Explanation:
Expected Number of Awards: 15
Assistance Listings: 93.173 — Research Related to Deafness and Communication Disorders
Cost Sharing or Matching Requirement: No
Version: Forecast 1
Posted Date: Mar 23, 2023
Last Updated Date:
Original Closing Date for Applications:
Current Closing Date for Applications:
Archive Date: Mar 13, 2023
Estimated Total Program Funding: $10,000,000
Award Ceiling:
Award Floor:

Eligibility

Eligible Applicants: Public and State controlled institutions of higher education
County governments
For profit organizations other than small businesses
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Independent school districts
Small businesses
Native American tribal organizations (other than Federally recognized tribal governments)
Native American tribal governments (Federally recognized)
Private institutions of higher education
Public housing authorities/Indian housing authorities
Others (see text field entitled “Additional Information on Eligibility” for clarification)
State governments
Additional Information on Eligibility:

Additional Information

Agency Name: National Institutes of Health
Description: The purpose of this notice is to inform applicants of the intention to re-issue�RFA-NS-21-026 and�RFA-NS-21-027, which were recently terminated. This Notice is being provided to alert potential applicants of anticipated changes in receipt dates and updated information on FOA requirements and goals.�Previously, both�RFA-NS-21-026 and�RFA-NS-21-027�included support for molecular constructs for recording and manipulating neural activity.�However, with the re-issued FOAs, projects primarily focused on molecular technologies will only be supported by the reissue of RFA-NS-21-026.� See below for details and potential alternative FOAs for consideration.� �
Link to Additional Information:
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact:


Email:-

Folder 346913 Full Announcement-RFA-NS-24-005 -> RFA-NS-24-005-Full-Announcement.pdf

Packages

Agency Contact Information: NIH Grants Information
grantsinfo@nih.gov
Email: grantsinfo@nih.gov
Who Can Apply: Organization Applicants

Assistance Listing Number Competition ID Competition Title Opportunity Package ID Opening Date Closing Date Actions
FORMS-H Use for due dates on or after January 25, 2023 PKG00280599 May 30, 2023 Sep 25, 2024 View

Package 1

Mandatory forms

346913 RR_SF424_5_0-5.0.pdf

346913 PHS398_CoverPageSupplement_5_0-5.0.pdf

346913 RR_OtherProjectInfo_1_4-1.4.pdf

346913 PerformanceSite_4_0-4.0.pdf

346913 RR_KeyPersonExpanded_4_0-4.0.pdf

346913 PHS398_ResearchPlan_5_0-5.0.pdf

346913 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf

Optional forms

346913 RR_Budget_3_0-3.0.pdf

346913 RR_SubawardBudget30_3_0-3.0.pdf

346913 PHS398_ModularBudget_1_2-1.2.pdf

346913 PHS_AssignmentRequestForm_3_0-3.0.pdf

2025-07-14T11:07:57-05:00

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