This grant, offered by the NIH HEAL Initiative, aims to support research focused on identifying new, druggable targets and discovering optimizable probes. The ultimate goal is to develop safe and efficacious medications for preventing and treating opioid use disorders (OUDs), opioid overdose, and related opioid-polysubstance use comorbidities. This funding opportunity is a crucial component of the NIH Helping to End Addictions Long-term (HEAL) initiative, designed to accelerate the development of innovative medications. These medications will address all facets of the opioid addiction cycle, including the progression to chronic use, managing withdrawal symptoms, reducing cravings, preventing relapse, and mitigating overdose risks. This initiative underscores a commitment to combating the opioid crisis through scientific advancement.
Opportunity ID: 334570
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DA-22-032 |
| Funding Opportunity Title: | HEAL Initiative: Novel Targets for Opioid Use Disorders and Opioid Overdose (R21 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.213 — Research and Training in Complementary and Integrative Health |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jul 06, 2021 |
| Last Updated Date: | Jul 06, 2021 |
| Original Closing Date for Applications: | Oct 19, 2021 |
| Current Closing Date for Applications: | Oct 19, 2021 |
| Archive Date: | Nov 24, 2021 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Others (see text field entitled “Additional Information on Eligibility” for clarification) State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments County governments Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments For profit organizations other than small businesses Independent school districts Public and State controlled institutions of higher education Small businesses Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this Funding Opportunity Announcement (FOA) is to support research projects focusing on the identification of druggable new targets and discovery of optimizable probes for development of safe and efficacious medications to prevent and treat opioid use disorders (OUDs), opioid overdose, and opioid-polysubstance use comorbidities. This FOA is part of the NIH Helping to End Addictions Long-term (HEAL) initiative to accelerate the development of novel medications to treat all aspects of the opioid addiction cycle, including progression to chronic use, withdrawal symptoms, craving, relapse, and overdose. https://heal.nih.gov/research/medication-options |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-22-032.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-F | Use for due dates on or before January 24, 2022 | PKG00268074 | Sep 19, 2021 | Jan 24, 2022 | View |
Package 1
Mandatory forms
334570 RR_SF424_2_0-2.0.pdf
334570 PHS398_CoverPageSupplement_5_0-5.0.pdf
334570 RR_OtherProjectInfo_1_4-1.4.pdf
334570 PerformanceSite_2_0-2.0.pdf
334570 RR_KeyPersonExpanded_2_0-2.0.pdf
334570 PHS398_ResearchPlan_4_0-4.0.pdf
334570 PHSHumanSubjectsAndClinicalTrialsInfo_2_0-2.0.pdf
Optional forms
334570 RR_Budget_1_4-1.4.pdf
334570 RR_SubawardBudget30_1_4-1.4.pdf
334570 PHS398_ModularBudget_1_2-1.2.pdf
334570 PHS_AssignmentRequestForm_3_0-3.0.pdf