This grant aims to support research exploring the intricate protective and pathogenic mechanisms at the intersection of mitochondrial function and the aging process, specifically within the context of HIV infection and exposure to addictive substances. The primary objective is to generate foundational knowledge crucial for understanding how mitochondrial health impacts neuropathological and immunodeficient aging in individuals living with HIV and substance use disorders. This essential research is anticipated to pave the way for the development of innovative, targeted therapies. Ultimately, the insights gained will contribute significantly to improving health outcomes and quality of life for people aging with HIV, substance use, and addiction, addressing critical public health challenges.
Opportunity ID: 356596
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DA-26-009 |
| Funding Opportunity Title: | Mitochondrial-associated Mechanisms of Neuropathological and Immunodeficient Aging in the Context of HIV and SUD (R01 Clinical Trials Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.279 — Drug Abuse and Addiction Research Programs |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Sep 30, 2024 |
| Last Updated Date: | Sep 30, 2024 |
| Original Closing Date for Applications: | Mar 10, 2026 |
| Current Closing Date for Applications: | Mar 10, 2026 |
| Archive Date: | Apr 15, 2026 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | For profit organizations other than small businesses Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) County governments Special district governments Independent school districts Small businesses State governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | To promote research investigating protective and pathogenic mechanisms at the nexus of mitochondria function and aging in the context of HIV infection and exposure to addictive substances. We anticipate this foundational knowledge could be leveraged to develop targeted therapies and improve outcomes in people aging with HIV, substance use and addiction. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-26-009.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 356596 Full Announcement-RFA-DA-26-009 -> RFA-DA-26-009-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00288384 | Feb 10, 2025 | Mar 10, 2026 | View |
Package 1
Mandatory forms
356596 RR_SF424_5_0-5.0.pdf
356596 PHS398_CoverPageSupplement_5_0-5.0.pdf
356596 RR_OtherProjectInfo_1_4-1.4.pdf
356596 PerformanceSite_4_0-4.0.pdf
356596 RR_KeyPersonExpanded_4_0-4.0.pdf
356596 PHS398_ResearchPlan_5_0-5.0.pdf
356596 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
356596 RR_Budget_3_0-3.0.pdf
356596 RR_SubawardBudget30_3_0-3.0.pdf
356596 PHS398_ModularBudget_1_2-1.2.pdf
356596 PHS_AssignmentRequestForm_4_0-4.0.pdf