The NIH is offering the Director’s Transformative Research Award to support individual or group scientists pursuing bold, groundbreaking, and exceptionally innovative research. This grant aims to foster new scientific paradigms, establish improved clinical approaches, or develop transformative technologies. Open to diverse applicants from all eligible institutions, projects can span all topics relevant to the broad NIH mission, including behavioral, social, biomedical, applied, and formal sciences, encompassing basic, translational, and clinical research. No preliminary data are required; proposals must demonstrate a compelling potential for major impact. This award is a component of the NIH Common Fund’s High-Risk, High-Reward Research Program, seeking to fund the best possible science by also piloting an anonymized peer review process.
Opportunity ID: 353035
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-RM-24-004 |
| Funding Opportunity Title: | NIH Directors Transformative Research Awards (R01 Clinical Trial Optional) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.310 — Trans-NIH Research Support |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Mar 18, 2024 |
| Last Updated Date: | Mar 18, 2024 |
| Original Closing Date for Applications: | Sep 03, 2024 |
| Current Closing Date for Applications: | Sep 03, 2024 |
| Archive Date: | Oct 09, 2024 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) Public housing authorities/Indian housing authorities Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) State governments Private institutions of higher education City or township governments County governments Small businesses For profit organizations other than small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The NIH Directors Transformative Research Award Program supports individual scientists or groups of scientists proposing bold, groundbreaking, exceptionally innovative, original, and/or unconventional research with the potential to create new scientific paradigms, establish entirely new and improved clinical approaches, or develop transformative technologies. To support innovative and novel research across the vast NIH mission, individuals from diverse backgrounds (including those from underrepresented groups; see Notice of NIHs Interest in Diversity) and from the full spectrum of eligible institutions in all geographic locations are encouraged to apply to this Notice of Funding Opportunity. Applications in all topics relevant to the broad mission of NIH are welcome in all topic areas relevant to the broad mission of NIH, including, but not limited to, behavioral, social, biomedical, applied, and formal sciences and topics that may involve basic, translational, or clinical research. No preliminary data are required. Projects must clearly demonstrate, based on the strength of the logic, a compelling potential to produce a major impact in a broad area of relevance to the NIH. The NIH Directors Transformative Research Award is a component of the High-Risk, High-Reward Research (HRHR) Program of the NIH Common Fund. Towards the objective of funding the best possible science, the Office of Strategic Coordination and the Center for Scientific Review are piloting a process for initial peer review of applications received in response to this FOA in which the identity of the investigators and institutions are withheld until the last phase of review. Instructions for anonymizing components of the application are given in Section IV and must be carefully followed. A description of the review process is given in Section V. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-RM-24-004.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 353035 Full Announcement-RFA-RM-24-004 -> RFA-RM-24-004-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00285426 | Aug 03, 2024 | Sep 03, 2024 | View |
Package 1
Mandatory forms
353035 RR_SF424_5_0-5.0.pdf
353035 PHS398_CoverPageSupplement_5_0-5.0.pdf
353035 RR_OtherProjectInfo_1_4-1.4.pdf
353035 PerformanceSite_4_0-4.0.pdf
353035 RR_KeyPersonExpanded_4_0-4.0.pdf
353035 PHS398_ResearchPlan_5_0-5.0.pdf
353035 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
353035 RR_Budget_3_0-3.0.pdf
353035 RR_SubawardBudget30_3_0-3.0.pdf
353035 PHS398_ModularBudget_1_2-1.2.pdf
353035 PHS_AssignmentRequestForm_3_0-3.0.pdf
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