This grant, the Nonhuman Primate Transplantation Tolerance Cooperative Study Group (NHPCSG), is for the purpose of establishing a multi-center, cooperative program. Its primary aim is to rigorously develop, optimize, and evaluate novel approaches to induce and maintain immune tolerance in allogeneic transplants, specifically utilizing nonhuman primate (NHP) models. The overarching objective of this initiative is to facilitate the critical clinical translation of these safe and effective tolerance-induction protocols. By doing so, it seeks to achieve significantly improved long-term graft survival in transplant recipients, bridging research from NHP studies to human application. This U01 mechanism supports essential collaborative efforts in transplantation.
Opportunity ID: 337415
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AI-22-002 |
| Funding Opportunity Title: | Nonhuman Primate Transplantation Tolerance Cooperative Study Group (U01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.855 — Allergy and Infectious Diseases Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jan 18, 2022 |
| Last Updated Date: | Jan 18, 2022 |
| Original Closing Date for Applications: | May 13, 2022 |
| Current Closing Date for Applications: | May 13, 2022 |
| Archive Date: | Jun 18, 2022 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Private institutions of higher education Special district governments Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) Small businesses State governments Public housing authorities/Indian housing authorities Others (see text field entitled “Additional Information on Eligibility” for clarification) Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses City or township governments Independent school districts County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This purpose of this RFA is to solicit applications for the Nonhuman Primate Transplantation Tolerance Cooperative Study Group (NHPCSG), a multi-center, cooperative program dedicated to developing, optimizing, and evaluating approaches to induce and maintain immune tolerance to allogeneic transplants in nonhuman primate (NHP) models. The over-arching goal is to facilitate clinical translation of safe and effective tolerance-induction protocols for long-term graft survival. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-AI-22-002.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
OERWebmaster03@od.nih.gov Email:OERWebmaster03@od.nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 337415 Full Announcement-RFA-AI-22-002 -> RFA-AI-22-002-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH OER Webmaster OERWebmaster03@od.nih.gov Email: OERWebmaster03@od.nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-G | Use for due dates on or after January 25, 2022 | PKG00271392 | Apr 13, 2022 | May 13, 2022 | View |
Package 1
Mandatory forms
337415 RR_SF424_5_0-5.0.pdf
337415 PHS398_CoverPageSupplement_5_0-5.0.pdf
337415 RR_OtherProjectInfo_1_4-1.4.pdf
337415 PerformanceSite_4_0-4.0.pdf
337415 RR_KeyPersonExpanded_4_0-4.0.pdf
337415 PHS398_ResearchPlan_4_0-4.0.pdf
337415 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
337415 RR_Budget_3_0-3.0.pdf
337415 RR_SubawardBudget30_3_0-3.0.pdf
337415 PHS398_ModularBudget_1_2-1.2.pdf
337415 PHS_AssignmentRequestForm_3_0-3.0.pdf
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