This grant, offered by the Paul D. Wellstone Muscular Dystrophy Program, seeks new and renewal applications for Muscular Dystrophy Cooperative Research Centers (MDCRCs). The purpose is to establish a network of centers fostering the translation of scientific discoveries into novel treatments for muscular dystrophies. This funding supports multi-disciplinary, collaborative research addressing critical gaps in the therapeutic development pipeline. Projects may encompass basic, translational, or clinical research, including therapeutic target identification, biomarker development, preclinical therapeutic optimization, FDA-required activities leading to investigational new drug (IND) applications, and early-stage clinical trials. The U54 Specialized Centers Cooperative Agreement mechanism supports these comprehensive efforts aimed at advancing treatments for various muscular dystrophy types.
Opportunity ID: 47345
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-HD-09-027 |
| Funding Opportunity Title: | Paul D. Wellstone Muscular Dystrophy Cooperative Research Centers (U54) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health Income Security and Social Services |
| Category Explanation: | – |
| Expected Number of Awards: | 3 |
| Assistance Listings: | 93.837 — Heart and Vascular Diseases Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | May 13, 2009 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Nov 10, 2009 |
| Current Closing Date for Applications: | Nov 10, 2009 |
| Archive Date: | Dec 11, 2009 |
| Estimated Total Program Funding: | $3,000,000 |
| Award Ceiling: | $1,000,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Private institutions of higher education Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) For profit organizations other than small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs). |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | Purpose. This funding opportunity announcement (FOA) solicits new (type 1) and competitive renewal (type 2) applications for the support of Paul D. Wellstone Muscular Dystrophy Cooperative Research Centers (MDCRCs). Successful applicants will join a network of existing Centers to foster the translation of new scientific findings and technological developments into novel treatments for the muscular dystrophies. Each Center may contain a mixture of basic, translational, or clinical research, as long as efforts are directed toward the steps required for therapeutic development, including therapeutic target identification, characterization, and validation, development of diagnostics and biomarkers to characterize or stratify patient populations, in vitro assay development, animal model development and characterization, candidate therapeutic efficacy screening, preclinical therapeutic optimization and FDA-required activities leading to an investigational new drug (IND) application, clinical infrastructure and studies in support of a clinical trial, patient-oriented natural history studies, and early stage clinical trials for one or more types of muscular dystrophy. Applicants should propose multi-disciplinary and collaborative studies that address one or more gaps in the therapeutic development pipeline for muscular dystrophy. Research problems should require substantial collaborative efforts to solve, and thus are best carried out in a center setting. Mechanism of Support. This FOA will utilize the U54 Specialized Centers Cooperative Agreement grant mechanism. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-HD-09-027.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
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