This grant is for advancing the understanding of adverse drug reactions (ADRs) in children. The Pediatric Pharmacology Research Department is offering this funding opportunity to support projects that enhance the state-of-the-science on the molecular, cellular, genetic, and epigenetic mechanisms involved in ADRs within the pediatric population. Research should explore the role of ontogeny and characterize pharmacogenetic and developmental variations in drug metabolizing enzymes, transporters, ion channels, receptors, and signaling pathways. The primary objective is to identify how these critical factors contribute to drug toxicity in children, ultimately improving drug safety and treatment outcomes for this vulnerable population.
Opportunity ID: 58962
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-11-051 |
| Funding Opportunity Title: | Mechanisms of Adverse Drug Reactions in Children (R01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health Income Security and Social Services |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.310 — Trans-NIH Research Support |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Dec 02, 2010 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | May 07, 2014 |
| Current Closing Date for Applications: | May 07, 2014 |
| Archive Date: | Jun 07, 2014 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Native American tribal governments (Federally recognized) City or township governments For profit organizations other than small businesses Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts County governments State governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education Public housing authorities/Indian housing authorities Special district governments Small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This FOA encourages projects that enhance the state-of-the-science on the molecular and cellular, genetic and epigenetic mechanisms involved in the production of adverse drug reactions in children. The objective of this announcement includes research on the role of ontogeny and the characterization of pharmacogenetic and developmental variations of drug metabolizing enzymes (DMEs), transporters, ion channels, receptors and signaling pathways that are responsible for drug toxicity in the pediatric population. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PAR-11-051.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| ADOBE-FORMS-B1 | ADOBE-FORMS-B1 | PKG00022712 | Feb 05, 2011 | Sep 24, 2013 | View | |
| FORMS-C | Use for due dates after 9/24/2013. | PKG00180569 | Sep 08, 2013 | May 07, 2014 | View |
Package 1
Mandatory forms
58962 RR_SF424_1_2-1.2.pdf
58962 RR_OtherProjectInfo_1_3-1.3.pdf
58962 RR_KeyPersonExpanded_1_2-1.2.pdf
58962 PerformanceSite_1_4-1.4.pdf
58962 PHS398_ResearchPlan_1_3-1.3.pdf
58962 PHS398_CoverPageSupplement_1_4-1.4.pdf
58962 PHS398_Checklist_1_3-1.3.pdf
Optional forms
58962 RR_Budget-1.1.pdf
58962 RR_SubawardBudget-1.2.pdf
58962 PHS_CoverLetter_1_2-1.2.pdf
58962 PHS398_ModularBudget-1.1.pdf
Package 2
Mandatory forms
58962 RR_SF424_2_0-2.0.pdf
58962 PHS398_ResearchPlan_2_0-2.0.pdf
58962 PHS398_CoverPageSupplement_2_0-2.0.pdf
58962 RR_KeyPersonExpanded_2_0-2.0.pdf
58962 RR_OtherProjectInfo_1_3-1.3.pdf
58962 PerformanceSite_2_0-2.0.pdf
Optional forms
58962 RR_SubawardBudget30_1_3-1.3.pdf
58962 PlannedReport-1.0.pdf
58962 PHS398_CumulativeInclusionReport-1.0.pdf
58962 PHS398_ModularBudget_1_2-1.2.pdf
58962 RR_Budget_1_3-1.3.pdf
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