This National Institutes of Health funding opportunity supports Early Stage Investigators (ESIs) conducting preclinical HIV/AIDS research with Nonhuman Primate (NHP) models. This grant is for ESIs within 10 years of their terminal degree or residency training, who also have a minimum of two years’ postdoctoral experience. The primary goal is to empower these researchers with independence, enabling them to establish new research directions and bolster their eligibility for subsequent research funding opportunities, such as R01 grants. All proposed projects are required to leverage NHPs as preclinical models. This initiative aligns with the full spectrum of priorities outlined in the NIH Strategic Plan for HIV, covering aspects from incidence reduction and next-generation therapies to cure research, managing associated comorbidities, and advancing broader scientific areas.
Opportunity ID: 357134
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-25-165 |
| Funding Opportunity Title: | Early Stage Investigator HIV/AIDS Research Using Nonhuman Primate (NHP) Models (R21 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.242 — Mental Health Research Grants |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Nov 15, 2024 |
| Last Updated Date: | Nov 15, 2024 |
| Original Closing Date for Applications: | Sep 07, 2025 |
| Current Closing Date for Applications: | Sep 07, 2025 |
| Archive Date: | Oct 13, 2025 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | For profit organizations other than small businesses State governments Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) County governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Special district governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Small businesses City or township governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this funding opportunity announcement (FOA) is to support preclinical HIV/AIDS research using NHP models performed by Early Stage Investigators (ESIs) who are within 10 years of their terminal degree or completion of their residency training but who have at least two years of postdoctoral experience. The goal of this support is to help advance HIV/AIDS researchers using NHP models in preclinical research by providing a degree of independence for these ESIs to develop new research directions and to position these researchers to be competitive for new research funding (e.g., R01). Proposed projects must use NHPs as preclinical models for HIV/AIDS research. This funding initiative encompasses all priorities of the fiscal year (FY) 2021-2025 NIH Strategic Plan for HIV and HIV-Related Research (https://www.oar.nih.gov/hiv-policy-and-research/strategic-plan): reduce the incidence of HIV; develop next-generation HIV therapies; conduct research toward HIV cure; address HIV-associated comorbidities, coinfections, and complications; and advance cross-cutting areas of research. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/pa-files/PAR-25-165.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 357134 Full Announcement-PAR-25-165 -> PAR-25-165-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00288729 | Apr 07, 2025 | Sep 07, 2025 | View |
Package 1
Mandatory forms
357134 RR_SF424_5_0-5.0.pdf
357134 PHS398_CoverPageSupplement_5_0-5.0.pdf
357134 RR_OtherProjectInfo_1_4-1.4.pdf
357134 PerformanceSite_4_0-4.0.pdf
357134 RR_KeyPersonExpanded_4_0-4.0.pdf
357134 PHS398_ResearchPlan_5_0-5.0.pdf
357134 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
357134 RR_Budget_3_0-3.0.pdf
357134 RR_SubawardBudget30_3_0-3.0.pdf
357134 PHS398_ModularBudget_1_2-1.2.pdf
357134 PHS_AssignmentRequestForm_4_0-4.0.pdf
Share This Post, Choose Your Platform!
About the Author: osnqt
