This grant invites applications to investigate the cellular and molecular mechanisms linking alcohol consumption to increased cancer risk. Recognized as carcinogenic by leading health organizations, alcohol contributes to cancers in the upper aerodigestive tract, breast, liver, and colon. The primary purpose of this funding is to gain a deeper understanding of the molecular basis by which alcohol promotes carcinogenesis in specific tissues and organs. Such knowledge is vital for developing improved therapeutic interventions and preventative strategies. Ultimately, this research will guide the establishment of safer alcohol consumption levels, contributing significantly to public health by reducing the incidence of alcohol-associated cancers.
Opportunity ID: 292436
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PA-17-220 |
| Funding Opportunity Title: | Mechanisms of Alcohol-associated Cancers (R01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.273 — Alcohol Research Programs |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Mar 13, 2017 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Sep 07, 2020 |
| Current Closing Date for Applications: | Sep 07, 2020 |
| Archive Date: | Oct 13, 2020 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Public and State controlled institutions of higher education City or township governments Special district governments For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Private institutions of higher education Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments Others (see text field entitled “Additional Information on Eligibility” for clarification) County governments Native American tribal governments (Federally recognized) Independent school districts |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) invites applications investigating the cellular and molecular mechanisms by which alcohol increases cancer risk. Alcohol consumption is classified as carcinogenic to humans by the International Agency for Research on Cancer (IARC; 2010, 2012) and the National Toxicology Program (NTP; 2014) of the US Department of Health and Human Services. Target sites for alcohol-related carcinogenesis include the upper aerodigestive tract, breast, liver, and colon. A better understanding of the molecular basis by which alcohol increases cancer risk for certain tissues and organs could lead to improved therapeutic approaches and preventative strategies and would provide guidance on safe levels of alcohol consumption. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PA-17-220.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-D | Use for due dates on or before January 24, 2018 | PKG00231370 | May 05, 2017 | Jan 24, 2018 | View | |
| FORMS-E | Use for due dates on or before May 24, 2020 | PKG00235901 | Nov 08, 2017 | May 24, 2020 | View | |
| FORMS-F | Use for due dates on or after May 25, 2020 | PKG00259223 | May 05, 2017 | Sep 07, 2020 | View |
Package 1
Mandatory forms
292436 RR_SF424_2_0-2.0.pdf
292436 PHS398_CoverPageSupplement_3_0-3.0.pdf
292436 RR_OtherProjectInfo_1_3-1.3.pdf
292436 PerformanceSite_2_0-2.0.pdf
292436 RR_KeyPersonExpanded_2_0-2.0.pdf
292436 PHS398_ResearchPlan_3_0-3.0.pdf
Optional forms
292436 RR_Budget_1_3-1.3.pdf
292436 RR_SubawardBudget30_1_3-1.3.pdf
292436 PHS398_ModularBudget_1_2-1.2.pdf
292436 PHS_Inclusion_Enrollment_Report-1.0.pdf
292436 PHS_AssignmentRequestForm-1.0.pdf
Package 2
Mandatory forms
292436 RR_SF424_2_0-2.0.pdf
292436 PHS398_CoverPageSupplement_4_0-4.0.pdf
292436 RR_OtherProjectInfo_1_4-1.4.pdf
292436 PerformanceSite_2_0-2.0.pdf
292436 RR_KeyPersonExpanded_2_0-2.0.pdf
292436 PHS398_ResearchPlan_4_0-4.0.pdf
Optional forms
292436 RR_Budget_1_4-1.4.pdf
292436 RR_SubawardBudget30_1_4-1.4.pdf
292436 PHS398_ModularBudget_1_2-1.2.pdf
292436 PHS_AssignmentRequestForm_2_0-2.0.pdf
Package 3
Mandatory forms
292436 RR_SF424_2_0-2.0.pdf
292436 PHS398_CoverPageSupplement_5_0-5.0.pdf
292436 RR_OtherProjectInfo_1_4-1.4.pdf
292436 PerformanceSite_2_0-2.0.pdf
292436 RR_KeyPersonExpanded_2_0-2.0.pdf
292436 PHS398_ResearchPlan_4_0-4.0.pdf
292436 PHSHumanSubjectsAndClinicalTrialsInfo_2_0-2.0.pdf
Optional forms
292436 RR_Budget_1_4-1.4.pdf
292436 RR_SubawardBudget30_1_4-1.4.pdf
292436 PHS398_ModularBudget_1_2-1.2.pdf
292436 PHS_AssignmentRequestForm_3_0-3.0.pdf
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