The United States Army Medical Research Acquisitions Activity (USAMRAA), under the Defense Health Program, is offering this grant to advance research into the critical association between Traumatic Brain Injury (TBI) and Alzheimer’s disease (AD). This grant is for the purpose of developing innovative research tools and clinical outcomes to improve the detection and diagnosis of neurological changes linked to TBI-associated AD, particularly within the military community. A key objective is also to foster technologies that enhance the quality of life for individuals experiencing neurological impairment from TBI or AD. This award specifically supports high-impact, population-based research aimed at benefiting both military personnel and the wider civilian population.
Opportunity ID: 202894
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | W81XWH-12-MRPRA-MRFA |
| Funding Opportunity Title: | FY12 Militarily Relevant Peer Reviewed Alzheimer’s Disease Research Program (MRPRA) Military Risk Factors Research Award |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement Grant |
| Category of Funding Activity: | Science and Technology and other Research and Development |
| Category Explanation: | – |
| Expected Number of Awards: | 1 |
| Assistance Listings: | 12.420 — Military Medical Research and Development |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 5 |
| Posted Date: | Sep 29, 2012 |
| Last Updated Date: | Nov 03, 2012 |
| Original Closing Date for Applications: | Feb 04, 2013 |
| Current Closing Date for Applications: | Feb 04, 2013 |
| Archive Date: | Mar 06, 2013 |
| Estimated Total Program Funding: | $6,400,000 |
| Award Ceiling: | $6,400,000 |
| Award Floor: | $0 |
Eligibility
| Eligible Applicants: | Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility” |
| Additional Information on Eligibility: | – |
Additional Information
| Agency Name: | Dept. of the Army — USAMRAA |
| Description: | Applications to the FY12 Militarily Relevant Peer Reviewed Alzheimers Disease ResearchProgram (MRPRA) are being solicited for the Assistant Secretary of Defense for Health Affairs,Defense Health Program Medical Research and Development Office by the UnitedStates Army Medical Research Acquisitions Activity (USAMRAA). The Telemedicine andAdvanced Technology Research Center (TATRC) is administering the application process, andUSAMRAA is issuing this Program Announcement and will be negotiating all resulting awards.Military personnel who suffer severe or moderate TBI face an increased risk for developingseveral long-term health problems. These conditions include Alzheimer’s-like dementia,aggression, memory loss, depression, and symptoms similar to those of other neurologicaldiseases. Even mild TBI may be associated with some of these adverse consequences.The mission of the MRPRA is to build an integrated program devoted towards understanding the association between Traumatic Brain Injury (TBI) and Alzheimers disease (AD), and reducingthe burden on those affected especially in the military community. Therefore, the primaryobjective of the FY12 MRPRA is to facilitate the development of research tools and clinicaloutcomes that will permit the detection and diagnosis of neurological change found with TBI associated AD. A second, but equally important, objective for the FY12 MRPRA is the development of technologies intended to directly benefit individuals suffering from the symptoms of neurological impairment associated with either TBI or AD. Research falling under this second objective is intended to either increase or maintain the quality of life of those affectedby the symptoms of either TBI or AD. Research funded through the Military Risk Factors Research Award (MRFA) Program Announcement/Funding Opportunity is intended to facilitate high-impact, systematic, population-based, research into the association between TBI and AD. The research impact is intended to benefit the military community, while meeting a public purpose for the benefit of the civilian community. Applications must detail the plan for providing access to the study cohort. Preliminary data which supports how the cohort will be used in the study is also required. The preliminary data should also strongly support the proposed research hypotheses. |
| Link to Additional Information: | – |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
Mary Rico
Grants Officer Email:programannouncements@tatrc.org |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
| This Prgram Announcement is modified only to extend the Pre-application deadline from November 5, 2012 to November 13, 2012. No other changes have been made. | Nov 03, 2012 | |
| The Program Announcement has been modified only to extend the Pre-application deadline to 5:00pm ET, November 5, 2012. No other changes have been effected. | Nov 03, 2012 | |
| This modification is only to revise the individual award ceiling to $6.4 million. | Oct 29, 2012 | |
| 10/02/12 – Modification to the Program Announcement was made to the Title Page only to revise the deadline time for Pre-applications to 5:00 p.m. ET, October 29, 2012 (from 11:59 p.m. ET, October 29, 2012). | Oct 16, 2012 | |
| Oct 02, 2012 |
DISPLAYING: Synopsis 5
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | W81XWH-12-MRPRA-MRFA |
| Funding Opportunity Title: | FY12 Militarily Relevant Peer Reviewed Alzheimer’s Disease Research Program (MRPRA) Military Risk Factors Research Award |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement Grant |
| Category of Funding Activity: | Science and Technology and other Research and Development |
| Category Explanation: | – |
| Expected Number of Awards: | 1 |
| Assistance Listings: | 12.420 — Military Medical Research and Development |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 5 |
| Posted Date: | Sep 29, 2012 |
| Last Updated Date: | Nov 03, 2012 |
| Original Closing Date for Applications: | Feb 04, 2013 |
| Current Closing Date for Applications: | Feb 04, 2013 |
| Archive Date: | Mar 06, 2013 |
| Estimated Total Program Funding: | $6,400,000 |
| Award Ceiling: | $6,400,000 |
| Award Floor: | $0 |
Eligibility
| Eligible Applicants: | Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility” |
| Additional Information on Eligibility: | – |
Additional Information
| Agency Name: | Dept. of the Army — USAMRAA |
| Description: | Applications to the FY12 Militarily Relevant Peer Reviewed Alzheimers Disease ResearchProgram (MRPRA) are being solicited for the Assistant Secretary of Defense for Health Affairs,Defense Health Program Medical Research and Development Office by the UnitedStates Army Medical Research Acquisitions Activity (USAMRAA). The Telemedicine andAdvanced Technology Research Center (TATRC) is administering the application process, andUSAMRAA is issuing this Program Announcement and will be negotiating all resulting awards.Military personnel who suffer severe or moderate TBI face an increased risk for developingseveral long-term health problems. These conditions include Alzheimer’s-like dementia,aggression, memory loss, depression, and symptoms similar to those of other neurologicaldiseases. Even mild TBI may be associated with some of these adverse consequences.The mission of the MRPRA is to build an integrated program devoted towards understanding the association between Traumatic Brain Injury (TBI) and Alzheimers disease (AD), and reducingthe burden on those affected especially in the military community. Therefore, the primaryobjective of the FY12 MRPRA is to facilitate the development of research tools and clinicaloutcomes that will permit the detection and diagnosis of neurological change found with TBI associated AD. A second, but equally important, objective for the FY12 MRPRA is the development of technologies intended to directly benefit individuals suffering from the symptoms of neurological impairment associated with either TBI or AD. Research falling under this second objective is intended to either increase or maintain the quality of life of those affectedby the symptoms of either TBI or AD. Research funded through the Military Risk Factors Research Award (MRFA) Program Announcement/Funding Opportunity is intended to facilitate high-impact, systematic, population-based, research into the association between TBI and AD. The research impact is intended to benefit the military community, while meeting a public purpose for the benefit of the civilian community. Applications must detail the plan for providing access to the study cohort. Preliminary data which supports how the cohort will be used in the study is also required. The preliminary data should also strongly support the proposed research hypotheses. |
| Link to Additional Information: | – |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
Mary Rico
Grants Officer Email:programannouncements@tatrc.org |
DISPLAYING: Synopsis 4
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | W81XWH-12-MRPRA-MRFA |
| Funding Opportunity Title: | FY12 Militarily Relevant Peer Reviewed Alzheimer’s Disease Research Program (MRPRA) Military Risk Factors Research Award |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement Grant |
| Category of Funding Activity: | Science and Technology and other Research and Development |
| Category Explanation: | – |
| Expected Number of Awards: | 1 |
| Assistance Listings: | 12.420 — Military Medical Research and Development |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 4 |
| Posted Date: | Nov 03, 2012 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | – |
| Current Closing Date for Applications: | Feb 04, 2013 |
| Archive Date: | Mar 06, 2013 |
| Estimated Total Program Funding: | $6,400,000 |
| Award Ceiling: | $6,400,000 |
| Award Floor: | $0 |
Eligibility
| Eligible Applicants: | Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility” |
| Additional Information on Eligibility: | – |
Additional Information
| Agency Name: | Dept. of the Army — USAMRAA |
| Description: | Applications to the FY12 Militarily Relevant Peer Reviewed Alzheimers Disease ResearchProgram (MRPRA) are being solicited for the Assistant Secretary of Defense for Health Affairs,Defense Health Program Medical Research and Development Office by the UnitedStates Army Medical Research Acquisitions Activity (USAMRAA). The Telemedicine andAdvanced Technology Research Center (TATRC) is administering the application process, andUSAMRAA is issuing this Program Announcement and will be negotiating all resulting awards.Military personnel who suffer severe or moderate TBI face an increased risk for developingseveral long-term health problems. These conditions include Alzheimer’s-like dementia,aggression, memory loss, depression, and symptoms similar to those of other neurologicaldiseases. Even mild TBI may be associated with some of these adverse consequences.The mission of the MRPRA is to build an integrated program devoted towards understanding the association between Traumatic Brain Injury (TBI) and Alzheimers disease (AD), and reducingthe burden on those affected especially in the military community. Therefore, the primaryobjective of the FY12 MRPRA is to facilitate the development of research tools and clinicaloutcomes that will permit the detection and diagnosis of neurological change found with TBI associated AD. A second, but equally important, objective for the FY12 MRPRA is the development of technologies intended to directly benefit individuals suffering from the symptoms of neurological impairment associated with either TBI or AD. Research falling under this second objective is intended to either increase or maintain the quality of life of those affectedby the symptoms of either TBI or AD. Research funded through the Military Risk Factors Research Award (MRFA) Program Announcement/Funding Opportunity is intended to facilitate high-impact, systematic, population-based, research into the association between TBI and AD. The research impact is intended to benefit the military community, while meeting a public purpose for the benefit of the civilian community. Applications must detail the plan for providing access to the study cohort. Preliminary data which supports how the cohort will be used in the study is also required. The preliminary data should also strongly support the proposed research hypotheses. |
| Link to Additional Information: | – |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
Mary Rico
Grants Officer Email:programannouncements@tatrc.org |
DISPLAYING: Synopsis 3
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | W81XWH-12-MRPRA-MRFA |
| Funding Opportunity Title: | FY12 Militarily Relevant Peer Reviewed Alzheimer’s Disease Research Program (MRPRA) Military Risk Factors Research Award |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement Grant |
| Category of Funding Activity: | Science and Technology and other Research and Development |
| Category Explanation: | – |
| Expected Number of Awards: | 1 |
| Assistance Listings: | 12.420 — Military Medical Research and Development |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 3 |
| Posted Date: | Oct 29, 2012 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | – |
| Current Closing Date for Applications: | Feb 04, 2013 |
| Archive Date: | Mar 06, 2013 |
| Estimated Total Program Funding: | $6,400,000 |
| Award Ceiling: | $6,400,000 |
| Award Floor: | $0 |
Eligibility
| Eligible Applicants: | Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility” |
| Additional Information on Eligibility: | – |
Additional Information
| Agency Name: | Dept. of the Army — USAMRAA |
| Description: | Applications to the FY12 Militarily Relevant Peer Reviewed Alzheimers Disease ResearchProgram (MRPRA) are being solicited for the Assistant Secretary of Defense for Health Affairs,Defense Health Program Medical Research and Development Office by the UnitedStates Army Medical Research Acquisitions Activity (USAMRAA). The Telemedicine andAdvanced Technology Research Center (TATRC) is administering the application process, andUSAMRAA is issuing this Program Announcement and will be negotiating all resulting awards.Military personnel who suffer severe or moderate TBI face an increased risk for developingseveral long-term health problems. These conditions include Alzheimer’s-like dementia,aggression, memory loss, depression, and symptoms similar to those of other neurologicaldiseases. Even mild TBI may be associated with some of these adverse consequences.The mission of the MRPRA is to build an integrated program devoted towards understanding the association between Traumatic Brain Injury (TBI) and Alzheimers disease (AD), and reducingthe burden on those affected especially in the military community. Therefore, the primaryobjective of the FY12 MRPRA is to facilitate the development of research tools and clinicaloutcomes that will permit the detection and diagnosis of neurological change found with TBI associated AD. A second, but equally important, objective for the FY12 MRPRA is the development of technologies intended to directly benefit individuals suffering from the symptoms of neurological impairment associated with either TBI or AD. Research falling under this second objective is intended to either increase or maintain the quality of life of those affectedby the symptoms of either TBI or AD. Research funded through the Military Risk Factors Research Award (MRFA) Program Announcement/Funding Opportunity is intended to facilitate high-impact, systematic, population-based, research into the association between TBI and AD. The research impact is intended to benefit the military community, while meeting a public purpose for the benefit of the civilian community. Applications must detail the plan for providing access to the study cohort. Preliminary data which supports how the cohort will be used in the study is also required. The preliminary data should also strongly support the proposed research hypotheses. |
| Link to Additional Information: | – |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
Mary Rico
Grants Officer Email:programannouncements@tatrc.org |
DISPLAYING: Synopsis 2
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | W81XWH-12-MRPRA-MRFA |
| Funding Opportunity Title: | FY12 Militarily Relevant Peer Reviewed Alzheimer’s Disease Research Program (MRPRA) Military Risk Factors Research Award |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement Grant |
| Category of Funding Activity: | Science and Technology and other Research and Development |
| Category Explanation: | – |
| Expected Number of Awards: | 1 |
| Assistance Listings: | 12.420 — Military Medical Research and Development |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 2 |
| Posted Date: | Oct 16, 2012 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | – |
| Current Closing Date for Applications: | Feb 04, 2013 |
| Archive Date: | Mar 06, 2013 |
| Estimated Total Program Funding: | $6,400,000 |
| Award Ceiling: | $4,000,000 |
| Award Floor: | $0 |
Eligibility
| Eligible Applicants: | Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility” |
| Additional Information on Eligibility: | – |
Additional Information
| Agency Name: | Dept. of the Army — USAMRAA |
| Description: | Applications to the FY12 Militarily Relevant Peer Reviewed Alzheimers Disease ResearchProgram (MRPRA) are being solicited for the Assistant Secretary of Defense for Health Affairs,Defense Health Program Medical Research and Development Office by the UnitedStates Army Medical Research Acquisitions Activity (USAMRAA). The Telemedicine andAdvanced Technology Research Center (TATRC) is administering the application process, andUSAMRAA is issuing this Program Announcement and will be negotiating all resulting awards.Military personnel who suffer severe or moderate TBI face an increased risk for developingseveral long-term health problems. These conditions include Alzheimer’s-like dementia,aggression, memory loss, depression, and symptoms similar to those of other neurologicaldiseases. Even mild TBI may be associated with some of these adverse consequences.The mission of the MRPRA is to build an integrated program devoted towards understanding the association between Traumatic Brain Injury (TBI) and Alzheimers disease (AD), and reducingthe burden on those affected especially in the military community. Therefore, the primaryobjective of the FY12 MRPRA is to facilitate the development of research tools and clinicaloutcomes that will permit the detection and diagnosis of neurological change found with TBI associated AD. A second, but equally important, objective for the FY12 MRPRA is the development of technologies intended to directly benefit individuals suffering from the symptoms of neurological impairment associated with either TBI or AD. Research falling under this second objective is intended to either increase or maintain the quality of life of those affectedby the symptoms of either TBI or AD. Research funded through the Military Risk Factors Research Award (MRFA) Program Announcement/Funding Opportunity is intended to facilitate high-impact, systematic, population-based, research into the association between TBI and AD. The research impact is intended to benefit the military community, while meeting a public purpose for the benefit of the civilian community. Applications must detail the plan for providing access to the study cohort. Preliminary data which supports how the cohort will be used in the study is also required. The preliminary data should also strongly support the proposed research hypotheses. |
| Link to Additional Information: | – |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
Mary Rico
Grants Officer Email:programannouncements@tatrc.org |
DISPLAYING: Synopsis 1
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | W81XWH-12-MRPRA-MRFA |
| Funding Opportunity Title: | FY12 Militarily Relevant Peer Reviewed Alzheimer’s Disease Research Program (MRPRA) Military Risk Factors Research Award |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement Grant |
| Category of Funding Activity: | Science and Technology and other Research and Development |
| Category Explanation: | – |
| Expected Number of Awards: | 1 |
| Assistance Listings: | 12.420 — Military Medical Research and Development |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Oct 02, 2012 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | – |
| Current Closing Date for Applications: | Feb 04, 2013 |
| Archive Date: | Mar 06, 2013 |
| Estimated Total Program Funding: | $6,400,000 |
| Award Ceiling: | $4,000,000 |
| Award Floor: | $0 |
Eligibility
| Eligible Applicants: | Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility” |
| Additional Information on Eligibility: | – |
Additional Information
| Agency Name: | Dept. of the Army — USAMRAA |
| Description: | Applications to the FY12 Militarily Relevant Peer Reviewed Alzheimers Disease Research Program (MRPRA) are being solicited for the Assistant Secretary of Defense for Health Affairs, Defense Health Program Medical Research and Development Office by the United States Army Medical Research Acquisitions Activity (USAMRAA). The Telemedicine and Advanced Technology Research Center (TATRC) is administering the application process, and USAMRAA is issuing this Program Announcement and will be negotiating all resulting awards. Military personnel who suffer severe or moderate TBI face an increased risk for developing several long-term health problems. These conditions include Alzheimer’s-like dementia, aggression, memory loss, depression, and symptoms similar to those of other neurological diseases. Even mild TBI may be associated with some of these adverse consequences. The mission of the MRPRA is to build an integrated program devoted towards understanding the association between Traumatic Brain Injury (TBI) and Alzheimers disease (AD), and reducing the burden on those affected especially in the military community. Therefore, the primary objective of the FY12 MRPRA is to facilitate the development of research tools and clinical outcomes that will permit the detection and diagnosis of neurological change found with TBI associated AD. A second, but equally important, objective for the FY12 MRPRA is the development of technologies intended to directly benefit individuals suffering from the symptoms of neurological impairment associated with either TBI or AD. Research falling under this second objective is intended to either increase or maintain the quality of life of those affected by the symptoms of either TBI or AD. Research funded through the Military Risk Factors Research Award (MRFA) Program Announcement/Funding Opportunity is intended to facilitate high-impact, systematic, population-based, research into the association between TBI and AD. The research impact is intended to benefit the military community, while meeting a public purpose for the benefit of the civilian community. Applications must detail the plan for providing access to the study cohort. Preliminary data which supports how the cohort will be used in the study is also required. The preliminary data should also strongly support the proposed research hypotheses. |
| Link to Additional Information: | – |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
Mary Rico
Grants Officer Email:programannouncements@tatrc.org |
Related Documents
Folder 202894 Full Announcement-1 -> biosketch.pdf
Folder 202894 Full Announcement-1 -> representations-for-assistance-agreements[1].pdf
Folder 202894 Full Announcement-1 -> mrfa application instructions.pdf
Folder 202894 Full Announcement-1 -> mrfa program announcement rvsd 11-03-12.pdf
Folder 202894 Full Announcement-1 -> abstract-form[1].pdf
Folder 202894 Full Announcement-1 -> certifications-and-assurances-for-assistance-agreements[1].pdf
Packages
| Agency Contact Information: | Mary Rico Grants Officer Email: programannouncements@tatrc.org |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| 12.420 | PKG00148371 | Sep 29, 2012 | Feb 04, 2013 | View |
Package 1
Mandatory forms
202894 RR_SF424_1_2-1.2.pdf
202894 RR_KeyPersonExpanded_1_2-1.2.pdf
202894 PerformanceSite_1_4-1.4.pdf
202894 RR_Budget-1.1.pdf
202894 RR_OtherProjectInfo_1_3-1.3.pdf
Optional forms
202894 RR_SubawardBudget-1.2.pdf
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