Opportunity ID: 279754

General Information

Document Type: Grants Notice
Funding Opportunity Number: W81XWH-15-NETPR-CPA
Funding Opportunity Title: Neurotoxin Exposure Treatment Parkinson’s Career Progression Award
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Grant
Category of Funding Activity: Science and Technology and other Research and Development
Category Explanation:
Expected Number of Awards: 3
Assistance Listings: 12.420 — Military Medical Research and Development
Cost Sharing or Matching Requirement: No
Version: Synopsis 2
Posted Date: Oct 22, 2015
Last Updated Date: Oct 26, 2015
Original Closing Date for Applications: Dec 16, 2015
Current Closing Date for Applications: Dec 16, 2015
Archive Date: Jan 15, 2016
Estimated Total Program Funding: $1,000,000
Award Ceiling:
Award Floor:

Eligibility

Eligible Applicants: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility”
Additional Information on Eligibility:

Additional Information

Agency Name: Dept. of the Army — USAMRAA
Description: Applications to the Fiscal Year 2015 (FY15) Neurotoxin Exposure Treatment Parkinson’s Research (NETPR) Program are being solicited by the U.S. Army Medical Research Acquisition Activity (USAMRAA). The executing agent for this Program Announcement/Funding Opportunity is the Congressionally Directed Medical Research Programs (CDMRP).The NETPR Program was initiated in FY97 to provide support for research of exceptional scientific merit leading to an understanding of the cause, prevention, and treatment of the loss of dopaminergic neurons in the Substantia nigra that result in Parkinson’s disease (PD).The mission of the NETPR Program is to:· Identify surrogate markers of PD,· Correlate distinctive clinical features with specific clusters of these markers, and· Develop interventions in bio-molecular pathways that link markers and expressed clinical features in order to prevent or halt progression of the disease or improve the quality of life for PD patients.This funding opportunity is specifically focused on the following Areas of Emphasis for non-motor manifestations in PD (e.g., cognitive impairment, depression, autonomic dysfunction, and sleep disturbance):· Identification of metabolic pathway alterations and/or therapeutic intervention points.· Identification of molecular markers.· Exploration of genetic alterations associated with functional expressions of non-motor manifestations of the sporadic (non-familial) form of PD.Innovative applications not focused on the Areas of Emphasis noted above are acceptable, provided the application:· Addresses the development or progression of one or more non-motor manifestations of PD; and· Provides a strong rationale for relevance to the mission of the NETPR Program. The Depression Research Award mechanism is being offered for the first time in FY15.The intent of the NETPR Program Career Progression Award is to support independent, early-career investigators who have innovative, high-impact ideas or new technologies applicable to PD research and/or patient care. This award provides an opportunity to obtain the funding and experience necessary for productive career progression at the forefront of research specifically on non-motor aspects of PD. Preliminary data to support the feasibility and rationale of the proposed work are required. Any preliminary data provided should be from the laboratory of the PI or collaborators.Key elements of the award mechanism are as follows:· Principal Investigator (PI): The PI’s record of achievements and the proposed research will be evaluated regarding his/her potential for contributing to the mission of the NETPR Program.· Areas of Emphasis: The proposed research must address at least one of the Areas of Emphasis.· Impact: The application must articulate how the proposed research will lead to the discovery and development of therapeutic interventions and/or lead to an improved quality of life for individuals with non-motor manifestations associated with PD. The research impact is intended to specifically benefit the PD population as well as Service Members and Veterans susceptible to, or living with, PD.
Link to Additional Information:
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

301-682-5507; help@cdmrp.org
Email:help@cdmrp.org

Version History

Version Modification Description Updated Date
Modification includes the Attachment 9 form, Career Progression Award Eligibility Statement. Oct 26, 2015
Oct 26, 2015

DISPLAYING: Synopsis 2

General Information

Document Type: Grants Notice
Funding Opportunity Number: W81XWH-15-NETPR-CPA
Funding Opportunity Title: Neurotoxin Exposure Treatment Parkinson’s Career Progression Award
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Grant
Category of Funding Activity: Science and Technology and other Research and Development
Category Explanation:
Expected Number of Awards: 3
Assistance Listings: 12.420 — Military Medical Research and Development
Cost Sharing or Matching Requirement: No
Version: Synopsis 2
Posted Date: Oct 22, 2015
Last Updated Date: Oct 26, 2015
Original Closing Date for Applications: Dec 16, 2015
Current Closing Date for Applications: Dec 16, 2015
Archive Date: Jan 15, 2016
Estimated Total Program Funding: $1,000,000
Award Ceiling:
Award Floor:

Eligibility

Eligible Applicants: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility”
Additional Information on Eligibility:

Additional Information

Agency Name: Dept. of the Army — USAMRAA
Description: Applications to the Fiscal Year 2015 (FY15) Neurotoxin Exposure Treatment Parkinson’s Research (NETPR) Program are being solicited by the U.S. Army Medical Research Acquisition Activity (USAMRAA). The executing agent for this Program Announcement/Funding Opportunity is the Congressionally Directed Medical Research Programs (CDMRP).The NETPR Program was initiated in FY97 to provide support for research of exceptional scientific merit leading to an understanding of the cause, prevention, and treatment of the loss of dopaminergic neurons in the Substantia nigra that result in Parkinson’s disease (PD).The mission of the NETPR Program is to:· Identify surrogate markers of PD,· Correlate distinctive clinical features with specific clusters of these markers, and· Develop interventions in bio-molecular pathways that link markers and expressed clinical features in order to prevent or halt progression of the disease or improve the quality of life for PD patients.This funding opportunity is specifically focused on the following Areas of Emphasis for non-motor manifestations in PD (e.g., cognitive impairment, depression, autonomic dysfunction, and sleep disturbance):· Identification of metabolic pathway alterations and/or therapeutic intervention points.· Identification of molecular markers.· Exploration of genetic alterations associated with functional expressions of non-motor manifestations of the sporadic (non-familial) form of PD.Innovative applications not focused on the Areas of Emphasis noted above are acceptable, provided the application:· Addresses the development or progression of one or more non-motor manifestations of PD; and· Provides a strong rationale for relevance to the mission of the NETPR Program. The Depression Research Award mechanism is being offered for the first time in FY15.The intent of the NETPR Program Career Progression Award is to support independent, early-career investigators who have innovative, high-impact ideas or new technologies applicable to PD research and/or patient care. This award provides an opportunity to obtain the funding and experience necessary for productive career progression at the forefront of research specifically on non-motor aspects of PD. Preliminary data to support the feasibility and rationale of the proposed work are required. Any preliminary data provided should be from the laboratory of the PI or collaborators.Key elements of the award mechanism are as follows:· Principal Investigator (PI): The PI’s record of achievements and the proposed research will be evaluated regarding his/her potential for contributing to the mission of the NETPR Program.· Areas of Emphasis: The proposed research must address at least one of the Areas of Emphasis.· Impact: The application must articulate how the proposed research will lead to the discovery and development of therapeutic interventions and/or lead to an improved quality of life for individuals with non-motor manifestations associated with PD. The research impact is intended to specifically benefit the PD population as well as Service Members and Veterans susceptible to, or living with, PD.
Link to Additional Information:
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

301-682-5507; help@cdmrp.org
Email:help@cdmrp.org

DISPLAYING: Synopsis 1

General Information

Document Type: Grants Notice
Funding Opportunity Number: W81XWH-15-NETPR-CPA
Funding Opportunity Title: Neurotoxin Exposure Treatment Parkinson’s Career Progression Award
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Grant
Category of Funding Activity: Science and Technology and other Research and Development
Category Explanation:
Expected Number of Awards: 3
Assistance Listings: 12.420 — Military Medical Research and Development
Cost Sharing or Matching Requirement: No
Version: Synopsis 1
Posted Date: Oct 26, 2015
Last Updated Date:
Original Closing Date for Applications:
Current Closing Date for Applications: Dec 16, 2015
Archive Date: Jan 15, 2016
Estimated Total Program Funding: $1,000,000
Award Ceiling:
Award Floor:

Eligibility

Eligible Applicants: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility”
Additional Information on Eligibility:

Additional Information

Agency Name: Dept. of the Army — USAMRAA
Description: Applications to the Fiscal Year 2015 (FY15) Neurotoxin Exposure Treatment Parkinson’s Research (NETPR) Program are being solicited by the U.S. Army Medical Research Acquisition Activity (USAMRAA). The executing agent for this Program Announcement/Funding Opportunity is the Congressionally Directed Medical Research Programs (CDMRP).
The NETPR Program was initiated in FY97 to provide support for research of exceptional scientific merit leading to an understanding of the cause, prevention, and treatment of the loss of dopaminergic neurons in the Substantia nigra that result in Parkinson’s disease (PD).
The mission of the NETPR Program is to:
· Identify surrogate markers of PD,
· Correlate distinctive clinical features with specific clusters of these markers, and
· Develop interventions in bio-molecular pathways that link markers and expressed clinical features in order to prevent or halt progression of the disease or improve the quality of life for PD patients.
This funding opportunity is specifically focused on the following Areas of Emphasis for non-motor manifestations in PD (e.g., cognitive impairment, depression, autonomic dysfunction, and sleep disturbance):

· Identification of metabolic pathway alterations and/or therapeutic intervention points.
· Identification of molecular markers.
· Exploration of genetic alterations associated with functional expressions of non-motor manifestations of the sporadic (non-familial) form of PD.
Innovative applications not focused on the Areas of Emphasis noted above are acceptable, provided the application:
· Addresses the development or progression of one or more non-motor manifestations of PD; and
· Provides a strong rationale for relevance to the mission of the NETPR Program.

The Depression Research Award mechanism is being offered for the first time in FY15.

The intent of the NETPR Program Career Progression Award is to support independent, early-career investigators who have innovative, high-impact ideas or new technologies applicable to PD research and/or patient care. This award provides an opportunity to obtain the funding and experience necessary for productive career progression at the forefront of research specifically on non-motor aspects of PD. Preliminary data to support the feasibility and rationale of the proposed work are required. Any preliminary data provided should be from the laboratory of the PI or collaborators.
Key elements of the award mechanism are as follows:
· Principal Investigator (PI): The PI’s record of achievements and the proposed research will be evaluated regarding his/her potential for contributing to the mission of the NETPR Program.
· Areas of Emphasis: The proposed research must address at least one of the Areas of Emphasis.
· Impact: The application must articulate how the proposed research will lead to the discovery and development of therapeutic interventions and/or lead to an improved quality of life for individuals with non-motor manifestations associated with PD. The research impact is intended to specifically benefit the PD population as well as Service Members and Veterans susceptible to, or living with, PD.

Link to Additional Information:
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

301-682-5507; help@cdmrp.org
Email:help@cdmrp.org

Folder 279754 Full Announcement-1 -> FY15 CDMRP GAI_DRAFT_Edited_31July2015_Approved.pdf

Folder 279754 Full Announcement-1 -> NETPR_FY15_CPA_PA_GG.pdf

Folder 279754 Full Announcement-2 -> NETPR FY15 Eligibility Statement.pdf

Packages

Agency Contact Information: 301-682-5507; help@cdmrp.org
Email: help@cdmrp.org
Who Can Apply: Organization Applicants

Assistance Listing Number Competition ID Competition Title Opportunity Package ID Opening Date Closing Date Actions
12.420 PKG00219279 Oct 22, 2015 Dec 16, 2015 View

Package 1

Mandatory forms

279754 RR_SF424_2_0-2.0.pdf

279754 RR_Budget_1_3-1.3.pdf

279754 RR_KeyPersonExpanded_2_0-2.0.pdf

279754 PerformanceSite_2_0-2.0.pdf

Optional forms

279754 RR_SubawardBudget30_1_3-1.3.pdf

2025-07-09T18:02:25-05:00

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