This funding opportunity, offered by the NIH Blueprint for Neuroscience Research, encourages applications for its Innovation Grants to Nurture Initial Translational Efforts (IGNITE). This grant is for developing novel in vitro and/or ex vivo assays and conducting iterative screening. Its purpose is to identify and characterize potential therapeutic agents for neurological or neuromuscular disorders. The IGNITE program aims to advance early-stage projects, preparing them to meet entry criteria for the Blueprint Neurotherapeutics Network (BPN) or other translational programs. This initiative accelerates the discovery and development of new treatments in neuroscience.
Opportunity ID: 356800
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-25-059 |
| Funding Opportunity Title: | Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Assay Development and Neurotherapeutic Agent Identification (R61/R33 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.853 — Extramural Research Programs in the Neurosciences and Neurological Disorders |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Oct 22, 2024 |
| Last Updated Date: | Oct 22, 2024 |
| Original Closing Date for Applications: | Oct 20, 2027 |
| Current Closing Date for Applications: | Oct 20, 2027 |
| Archive Date: | Nov 25, 2027 |
| Estimated Total Program Funding: | $750,000 |
| Award Ceiling: | $750,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Public housing authorities/Indian housing authorities For profit organizations other than small businesses City or township governments Small businesses Independent school districts Special district governments Public and State controlled institutions of higher education Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) State governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This funding opportunity announcement (FOA) encourages research grant applications to develop in vitro and/or ex vivo assays and conduct iterative screening efforts to identify and characterize potential therapeutic agents for neurological or neuromuscular disorders. This FOA is part of a suite of Innovation Grants to Nurture Initial Translational Efforts (IGNITE) to advance projects to the point where they can meet the entry criteria for the Blueprint Neurotherapeutics Network (BPN) or other translational programs. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/pa-files/PAR-25-059.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 356800 Full Announcement-PAR-25-059 -> PAR-25-059-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00288421 | Jan 18, 2025 | Oct 20, 2027 | View |
Package 1
Mandatory forms
356800 RR_SF424_5_0-5.0.pdf
356800 PHS398_CoverPageSupplement_5_0-5.0.pdf
356800 RR_OtherProjectInfo_1_4-1.4.pdf
356800 PerformanceSite_4_0-4.0.pdf
356800 RR_KeyPersonExpanded_4_0-4.0.pdf
356800 RR_Budget10_3_0-3.0.pdf
356800 PHS398_ResearchPlan_5_0-5.0.pdf
356800 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
356800 RR_SubawardBudget10_30_3_0-3.0.pdf
356800 PHS_AssignmentRequestForm_4_0-4.0.pdf
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