The National Institutes of Health is offering a grant to support research on the mechanistic role of the microbiome in heart, lung, blood, and sleep diseases. This funding opportunity aims to uncover how the microbiota and its components influence HLBS biology and physiology, either promoting health or contributing to disease. Researchers are encouraged to conduct mechanistic studies using various models to understand how the microbiome interacts with host pathways. The goal is to provide insights for improved understanding and treatment of HLBS conditions in both adults and children. Multidisciplinary collaborations across scientific disciplines are encouraged. Closing date: Sep 07, 2021.
Opportunity ID: 305138
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PA-18-784 |
| Funding Opportunity Title: | The Mechanistic Role of the Microbiome in the Pathobiology of Heart, Lung, Blood, and Sleep Diseases (R01 – Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.233 — National Center on Sleep Disorders Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | May 15, 2018 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Sep 07, 2021 |
| Current Closing Date for Applications: | Sep 07, 2021 |
| Archive Date: | Oct 13, 2021 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Private institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) State governments City or township governments Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) County governments Native American tribal organizations (other than Federally recognized tribal governments) Public housing authorities/Indian housing authorities Small businesses For profit organizations other than small businesses Independent school districts Special district governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this funding opportunity announcement (FOA) is to support functional microbiome research focused on understanding the molecular, immunological and physiological mechanisms by which the microbiota (gut, lung, oral, including bacteria, viral and fungal microflora) and its derived factors modulate heart, lung, blood and sleep (HLBS) biology and physiology to promote health or contribute to disease. This FOA encourages mechanistic studies using in vitro, in vivo and/or ex vivo models that focus on the mechanistic and functional involvement of the microbiome and their components in the modulation or activation of host pathways. The goal is to provide the critical knowledge to guide early translational approaches for better understanding and treatment of HLBS conditions in adults and children. This FOA encourages multidisciplinary collaborations among scientists in a wide range of disciplines including (but not limited to) cardiology, pulmonology, hematology, sleep science, circadian biology, immunology, ‘-omic’ sciences, microbiology, microbial ecology, biotechnology, and bioinformatics. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PA-18-784.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-E | Use for due dates on or before May 24, 2020 | PKG00242119 | Sep 05, 2018 | May 24, 2020 | View | |
| FORMS-F | Use for due dates on or after May 25, 2020 | PKG00259120 | Sep 05, 2018 | Sep 07, 2021 | View |
Package 1
Mandatory forms
305138 RR_SF424_2_0-2.0.pdf
305138 PHS398_CoverPageSupplement_4_0-4.0.pdf
305138 RR_OtherProjectInfo_1_4-1.4.pdf
305138 PerformanceSite_2_0-2.0.pdf
305138 RR_KeyPersonExpanded_2_0-2.0.pdf
305138 PHS398_ResearchPlan_4_0-4.0.pdf
Optional forms
305138 RR_Budget_1_4-1.4.pdf
305138 RR_SubawardBudget30_1_4-1.4.pdf
305138 PHS398_ModularBudget_1_2-1.2.pdf
305138 PHS_AssignmentRequestForm_2_0-2.0.pdf
Package 2
Mandatory forms
305138 RR_SF424_2_0-2.0.pdf
305138 PHS398_CoverPageSupplement_5_0-5.0.pdf
305138 RR_OtherProjectInfo_1_4-1.4.pdf
305138 PerformanceSite_2_0-2.0.pdf
305138 RR_KeyPersonExpanded_2_0-2.0.pdf
305138 PHS398_ResearchPlan_4_0-4.0.pdf
305138 PHSHumanSubjectsAndClinicalTrialsInfo_2_0-2.0.pdf
Optional forms
305138 RR_Budget_1_4-1.4.pdf
305138 RR_SubawardBudget30_1_4-1.4.pdf
305138 PHS398_ModularBudget_1_2-1.2.pdf
305138 PHS_AssignmentRequestForm_3_0-3.0.pdf
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