This NIH grant is for supporting pilot clinical trials aimed at eliminating the latent HIV reservoir. It seeks applications evaluating interventions in HIV-infected adults who are on suppressive antiretroviral therapy. A core requirement is that these trials must fully integrate sophisticated laboratory-based analytical tools. These tools are essential for the precise detection and measurement of latently-infected cells, both within blood and tissue samples. The purpose of this grant is to drive forward research into novel strategies that could ultimately lead to the eradication of the persistent HIV reservoir, offering a pathway towards a functional cure for HIV.
Opportunity ID: 245353
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AI-13-055 |
| Funding Opportunity Title: | Pilot Clinical Trials to Eliminate the Latent HIV Reservoir (U01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.855 — Allergy, Immunology and Transplantation Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 2 |
| Posted Date: | Oct 24, 2013 |
| Last Updated Date: | Nov 25, 2013 |
| Original Closing Date for Applications: | Mar 07, 2014 |
| Current Closing Date for Applications: | Jul 15, 2014 |
| Archive Date: | Aug 15, 2014 |
| Estimated Total Program Funding: | $4,000,000 |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Native American tribal governments (Federally recognized) Others (see text field entitled “Additional Information on Eligibility” for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Native American tribal organizations (other than Federally recognized tribal governments) State governments Public housing authorities/Indian housing authorities Small businesses County governments Private institutions of higher education For profit organizations other than small businesses City or township governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) solicits applications for support of pilot clinical trials to evaluate interventions aimed at the elimination of the HIV reservoir in HIV-infected adults who are on suppressive antiretroviral therapy. It is expected that the trials will be fully integrated with laboratory-based analytical tools to detect and measure elimination of latently-infected cells both in blood and in tissue. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-AI-13-055.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
| Modified Archive Date based on new Expiration Date, per NOT-AI-14-014. | Nov 25, 2013 | |
| Nov 25, 2013 |
DISPLAYING: Synopsis 2
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AI-13-055 |
| Funding Opportunity Title: | Pilot Clinical Trials to Eliminate the Latent HIV Reservoir (U01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.855 — Allergy, Immunology and Transplantation Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 2 |
| Posted Date: | Oct 24, 2013 |
| Last Updated Date: | Nov 25, 2013 |
| Original Closing Date for Applications: | Mar 07, 2014 |
| Current Closing Date for Applications: | Jul 15, 2014 |
| Archive Date: | Aug 15, 2014 |
| Estimated Total Program Funding: | $4,000,000 |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Native American tribal governments (Federally recognized) Others (see text field entitled “Additional Information on Eligibility” for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Native American tribal organizations (other than Federally recognized tribal governments) State governments Public housing authorities/Indian housing authorities Small businesses County governments Private institutions of higher education For profit organizations other than small businesses City or township governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) solicits applications for support of pilot clinical trials to evaluate interventions aimed at the elimination of the HIV reservoir in HIV-infected adults who are on suppressive antiretroviral therapy. It is expected that the trials will be fully integrated with laboratory-based analytical tools to detect and measure elimination of latently-infected cells both in blood and in tissue. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-AI-13-055.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
DISPLAYING: Synopsis 1
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AI-13-055 |
| Funding Opportunity Title: | Pilot Clinical Trials to Eliminate the Latent HIV Reservoir (U01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.855 — Allergy, Immunology and Transplantation Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Nov 25, 2013 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | – |
| Current Closing Date for Applications: | Mar 07, 2014 |
| Archive Date: | Apr 07, 2014 |
| Estimated Total Program Funding: | $4,000,000 |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Special district governments City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Private institutions of higher education For profit organizations other than small businesses Public and State controlled institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments Native American tribal governments (Federally recognized) Small businesses Independent school districts County governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) solicits applications for support of pilot clinical trials to evaluate interventions aimed at the elimination of the HIV reservoir in HIV-infected adults who are on suppressive antiretroviral therapy. It is expected that the trials will be fully integrated with laboratory-based analytical tools to detect and measure elimination of latently-infected cells both in blood and in tissue. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-AI-13-055.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-C | Forms-C | PKG00187590 | Feb 07, 2014 | Jul 15, 2014 | View |
Package 1
Mandatory forms
245353 RR_SF424_2_0-2.0.pdf
245353 PHS398_ResearchPlan_2_0-2.0.pdf
245353 PHS398_CoverPageSupplement_2_0-2.0.pdf
245353 RR_KeyPersonExpanded_2_0-2.0.pdf
245353 RR_OtherProjectInfo_1_3-1.3.pdf
245353 PerformanceSite_2_0-2.0.pdf
Optional forms
245353 RR_SubawardBudget30_1_3-1.3.pdf
245353 PlannedReport-1.0.pdf
245353 PHS398_CumulativeInclusionReport-1.0.pdf
245353 PHS398_ModularBudget_1_2-1.2.pdf
245353 RR_Budget_1_3-1.3.pdf
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